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TranscriptomicsExpression data from 3 gamma-secretase or mock-treated mantle cell lymphoma (MCL) cell lines
We identified recurrent NOTCH1 mutations in 12% of MCLs. 2 out of 10 tested MCL cell lines (Rec-1 and SP-49) were sensitive to inhibition of the NOTCH pathway by gamma-secretase inhibition. The aim of this study was to identify transcriptional targets of NOTCH signaling in MCL. 3 MCL cell lines (Min...
ORGANISM(S): Homo sapiens 
2011-12-22 | E-GEOD-34602 | biostudies-arrayexpress
UnknownGene expression-based model using formalin-fixed paraffin-embedded biopsies predicts overall survival in advanced-stage classical Hodgkin lymphoma.
Not available
S-EPMC3574267 | biostudies-literature
UnknownFOXP1 expression is a prognostic biomarker in follicular lymphoma treated with rituximab and chemotherapy.
Not available
S-EPMC5757687 | biostudies-literature
Genomicsena-DATASET-BCCA-06-12-2013-17:57:13:627-21 - samples
Complete set of bam files associated with study EGAS00001000622
EGAD00001000702 | EGA
GenomicsPharmacological and genomic profiling identifies NFκB-targeted treatment strategies for mantle cell lymphoma
Mantle cell lymphoma (MCL) is an aggressive malignancy characterized by poor prognosis, underscoring the need for novel therapeutic strategies1. In this study, we employed large-scale pharmacological profiling of 16 pathway inhibitors across more than 100 hematological cell line models to identify n...
EGAS00001000622 | EGA
UnknownPARP14 is a novel target in STAT6 mutant follicular lymphoma.
Not available
S-EPMC9417990 | biostudies-literature
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