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UnknownClassroom-based physical activity improves children's math achievement - A randomized controlled trial.
Not available
S-EPMC6296522 | biostudies-literature
UnknownPlacental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1.
Not available
S-EPMC4996535 | biostudies-literature
TranscriptomicsWhole-genome sequencing of polyamine over-producing yeast strains
Dataset aims to uncover beneficial mutations on yeast strains (CEN.PK 113-11D based) engineered for polyamine over-production. We observed substantial heterogeneity between colony sizes and polyamine titers obtained between parent and final strains. Further physiological characterization of re-strea...
ORGANISM(S): Saccharomyces cerevisiae 
2021-03-31 | E-MTAB-9898 | biostudies-arrayexpress
TranscriptomicsCoupled single-cell RNA, TCR, and barcoded pMHC multimer sequencing, from virus-specific PBMC T-cells
Virus-specific CD8 T cells from PBMCs of healthy donors and hepatitis patients were enriched for recognition of a panel of feature barcode-labeled pMHC multimers. The phenotypic description was made using gene expression and TCRseq. Samples were pooled and sequenced on the same 10x Genomics sequenci...
ORGANISM(S): Homo sapiens 
2024-05-01 | E-MTAB-13758 | biostudies-arrayexpress
ProteomicsA microbial supply chain for production of anti-cancer drug vinblastine
Monoterpene indole alkaloids (MIAs) are a diverse family of complex plant secondary metabolites with many medicinal properties, including the essential anti-cancer therapeutics vinblastine and vincristine. As MIAs are difficult to chemically synthesize, the world’s supply chain for vinblastine relie...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-08-21 | PXD025067 | Pride
Yeast synthetic biology Monoterpene indole alkaloids Natural products 
GenomicsSimultaneous in vivo enzyme and host engineering through laboratory evolution
Two genetic selection systems that couple metabolite hydroxylation or methylation of small molecules to growth of Escherichia coli are presented in this study. One system targets pterin-dependent hydroxylation (tBPt) while another focuses on S-adenosylmethionine-dependent methylation (SAM). Using ad...
ORGANISM(S): Escherichia coli BW25113 
2019-01-30 | E-MTAB-6779 | biostudies-arrayexpress
UnknownAge- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.
Not available
S-EPMC5019754 | biostudies-literature
TranscriptomicsMolecular features of subtype-specific progression from ductal carcinoma in situ to invasive breast cancer [miRNA data]
Breast cancer consists of at least five main molecular “intrinsic” subtypes, which are reflected in both pre-invasive and invasive disease. Although previous studies have suggested that many of the molecular features of invasive breast cancer are established early, it is unclear what mechanisms ...
ORGANISM(S): Homo sapiens 
2016-07-07 | E-GEOD-59247 | biostudies-arrayexpress
TranscriptomicsMolecular features of subtype-specific progression from ductal carcinoma in situ to invasive breast cancer [gene expression data]
Breast cancer consists of at least five main molecular “intrinsic” subtypes, which are reflected in both pre-invasive and invasive disease. Although previous studies have suggested that many of the molecular features of invasive breast cancer are established early, it is unclear what mechanisms ...
ORGANISM(S): Homo sapiens 
2016-07-07 | E-GEOD-59246 | biostudies-arrayexpress
UnknownIntegrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis.
Not available
S-EPMC11096111 | biostudies-literature
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