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MetabolomicsDeficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease
Non-alcoholic fatty liver is the most common liver disease worldwide. Here, we show that the mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 expression was detected in liver biopsies from patients with non-alcoholic steatohepatitis (NASH). Moreover, reduced Mfn2...
2018-01-25 | MTBLS600 | MetaboLights
MetabolomicsDeep longitudinal multi-omics analysis of Bordetella pertussis cultivated in bioreactors highlights medium starvations and transitory metabolisms, associated to vaccine antigen biosynthesis variations and global virulence regulation

Bordetella pertussis is the bacterial causative agent of whooping cough, a serious respiratory illness. An extensive knowledge on its virulence regulation and metabolism is a key factor to ensure pertussis vaccine manufacturing process robustness. The aim of this study was to refine our ...

2023-02-21 | MTBLS5762 | MetaboLights
UnknownOn the pathway of cellular uptake: new insight into the interaction between the cell membrane and very small nanoparticles.
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S-EPMC5082453 | biostudies-literature
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S-EPMC5052662 | biostudies-literature
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S-EPMC6689170 | biostudies-literature
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S-EPMC7138754 | biostudies-literature
UnknownPomegranate Extracts in the Management of Men's Urologic Health: Scientific Rationale and Preclinical and Clinical Data.
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S-EPMC3622365 | biostudies-literature
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S-EPMC7183821 | biostudies-literature
UnknownEffects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults: A pilot study.
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S-EPMC6004924 | biostudies-literature
UnknownLow Mutation Burden in Ovarian Cancer May Limit the Utility of Neoantigen-Targeted Vaccines.
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S-EPMC4871527 | biostudies-literature
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