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TranscriptomicsMigration and invasion of 5 glioblastoma cell lines
Glioblastoma cells are characterized by a highly invasive behavior whose mechanisms are not yet understood. Using the wound healing and Boyden chamber assays we compared in the present study the migration and invasion abilities of 5 glioblastoma cell lines (DK-MG, GaMG, U87-MG, U373-MG, SNB19) diffe...
ORGANISM(S): Homo sapiens 
2014-09-05 | E-GEOD-53124 | biostudies-arrayexpress
TranscriptomicsMiz1 is required to maintain autophagic flux_2
To isolate neuronal progenitor cells (NPCs), forebrains of E13.5 Miz1+/+ or Miz1-delta-POZ embryos were cut in small pieces, digested with trypsin and filtered through sterile gauze. Cells were cultivated in 2:1 DMEM/F12 supplemented with 1xB27 (Life technologies), 20 ng/ul EGF (Biomol), 20 ng/?l ba...
ORGANISM(S): Mus musculus 
2013-10-01 | E-MEXP-3883 | biostudies-arrayexpress
TranscriptomicsMiz1 is required to maintain physiological levels of autophagic flux_1
Mice: knock-out of the Miz1 POZ-domain in brain (Miz1DPOZNes) and control mice. The RNA expression in cerebella of of old Miz1 delta POZ mice (1.5 years), old control mice (1.5 years), young Miz1 delta POZ mice (5.5 weeks) and young control mice (5.5 weeks) was compared
ORGANISM(S): Mus musculus 
2013-10-01 | E-MEXP-3878 | biostudies-arrayexpress
GenomicsMiz1 is required to maintain autophagic flux
Miz1 is a zinc finger protein that regulates expression of cell cycle inhibitors as part of a complex with Myc. Cell cycle-independent functions of Miz1 are poorly understood. Here, we use a Nestin-Cre transgene to delete an essential domain of Miz1 in the central nervous system (Miz1M-NM-^TPOZNes)....
ORGANISM(S): Homo sapiens 
2013-09-27 | E-GEOD-48602 | biostudies-arrayexpress
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