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TranscriptomicsTranscriptome of inflammatory myeloid DCs in psoriasis
Background: Previous work has identified CD11c+CD1c- dendritic cells (DCs) as the major 'inflammatory' dermal DC population in psoriasis vulgaris and CD1c+ DCs as the 'resident' cutaneous DC population. Objective: To further define molecular differences between these two myeloid dermal DC populatio...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-20264 | biostudies-arrayexpress
TranscriptomicsCombined Use of Laser Capture Microdissection and Microarray Analysis Identifies Locally Expressed Disease-Related Genes in Focal Regions of Psoriasis Vulgaris Skin Lesions
In this study, we sought to establish the usefulness of LCM on cDNA microarray analysis. We reported that LCM samples improved the sensitivity of detection of differentially expressed genes over conventional bulk tissue analysis. We also provided the new information of chemokine and its receptor int...
ORGANISM(S): Homo sapiens 
2012-01-30 | E-GEOD-26866 | biostudies-arrayexpress
TranscriptomicsA single intradermal injection of IFN-gamma induces a psoriasis-like state in both non-lesional psoriatic and healthy skin
Psoriasis is a chronic, debilitating, immune-mediated inflammatory skin disease. As IFN-gamma is involved in many cellular processes, including activation of T cells and dendritic cells (DCs), antigen processing and presentation, cell adhesion and trafficking, and cytokine and chemokine production, ...
ORGANISM(S): Homo sapiens 
2011-11-30 | E-GEOD-32407 | biostudies-arrayexpress
UnknownThe rationale for Janus kinase inhibitors for the treatment of spondyloarthritis.
Not available
S-EPMC6343466 | biostudies-literature
TranscriptomicsTranscription profiling of human response to etanercept treatment in patients with Psoriasis
The success of TNF inhibitors for treatment of psoriasis and other inflammatory diseases was previously attributed to blockade of innate immunity. In a clinical trial using etanercept TNF blocking agent to treat psoriasis vulgaris, we used affymetrix gene arrays to analyze broad gene profiles in le...
ORGANISM(S): Homo sapiens 
2009-11-09 | E-GEOD-11903 | biostudies-arrayexpress
UnknownThe Characterization of Varicella Zoster Virus-Specific T Cells in Skin and Blood during Aging.
Not available
S-EPMC4471118 | biostudies-literature
UnknownImmune and barrier characterization of atopic dermatitis skin phenotype in Tanzanian patients.
Not available
S-EPMC11344219 | biostudies-literature
UnknownThe human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses.
Not available
S-EPMC6122964 | biostudies-literature
UnknownMeta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking.
Not available
S-EPMC3309493 | biostudies-literature
UnknownMeta-analysis of genome-wide association studies for personality.
Not available
S-EPMC3785122 | biostudies-literature
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