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ProteomicsProteomics, post-translational modifications, and integrative analyses reveal heterogeneity of molecular mechanisms within medulloblastoma subgroups
Archer TC, Ehrenberger T, Mundt F, Gold MP, Krug K, Mah CK, Mahoney EL, Daniel CJ, LeNail A, Ramamoorthy D, Mertins P, Mani DR, Zhang H, Gillette MA, Clauser K, Noble M, Tang LC, Francois JP, Silterra J, Jensen J, Tamayo P, Korshunov A, Pfister SM, Kool M, Northcott PA, Sears RC, Lipton JO, Carr SA,...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-07-20 | MSV000082644 | MassIVE
ProteomicsMass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancer

Filip Mundt, Sandeep Rajput, Shunqiang Li, Kelly Ruggles, Arshag D. Mooradian, Philipp Mertins, Michael A. Gillette, Karsten Krug, et al., Cancer Res. 2018 May 15;78(10):2732-2746. doi: 10.1158/0008-5472.CAN-17-1990.

Activation of phosphoinositide 3-kinase (PI3K) signaling is frequently obs...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-10-19 | MSV000083050 | MassIVE
ProteomicsReproducible Workflow for Multiplexed Deep-Scale Proteome and Phosphoproteome Analysis of Tumor Tissues by Liquid Chromatography-Mass Spectrometry

Mertins P, Tang LC, Krug K, Clark DJ, Gritsenko MA, Chen L, Clauser KR, Clauss TR, Shah P, Gillette MA, et al., Nat Protoc. 2018 Jul 9. doi: 10.1038/s41596-018-0006-9

Here we present an optimized workflow for gl...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-30 | MSV000084265 | MassIVE
TranscriptomicsTranscriptome profile of mouse lung dendritic cell subsets and macrophages.
Dendritic cell (DC) are critical initiators and regulators of immunity to pathogens, vaccines, tumors and tolerance to self. Mouse and human dendritic cells (DCs) are comprised of functionally specialized subsets, but precise interspecies correlation is currently incomplete and hampers the full tra...
ORGANISM(S): Mus musculus 
2013-05-29 | E-GEOD-46680 | biostudies-arrayexpress
UnknownInternal Medicine Residents' Perceptions of Virtual Morning Report: a Multicenter Survey.
Not available
S-EPMC8231750 | biostudies-literature
ProteomicsProteogenomic Landscape Of Breast Cancer Tumorigenesis And Targeted Therapy
Karsten Krug, Eric J. Jaehnig, Shankha Satpathy, Lili Blumenberg, Alla Karpova, Meenakshi Anurag et al., (2020) Cell, 183, 1436-1456
DOI: https://doi.org/10.1016/j.cell.2020.10.036

The integration of ...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-06-05 | MSV000087576 | MassIVE
ProteomicsProteogenomics Connects Somatic Mutations to Signalling in Breast Cancer
Explore This Study at the NCI Proteomic Data Commons

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-28 | MSV000084248 | MassIVE
ProteomicsHighly multiplexed quantitative phosphosite assay for biology and preclinical studies
Reliable methods to quantify dynamic signaling changes across diverse pathways are needed to better understand the effects of disease and drug treatment in cells and tissues but are presently lacking. Here we present SigPath, a targeted mass spectrometry (MS) assay that measures 284 phosphosites in ...
ORGANISM(S): Homo Sapiens 
2021-10-08 | PXD026939 | panorama
TranscriptomicsGenome wide analysis of Histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene
Epigenetic deregulation plays a critical role in the pathogenesis of Acute Myeloid Leukemia. But changes in histone modification patterns at the epigenome level still remain largely unknown. Here, we analyzed alterations of histone H3 acetylation patterns in a large number of patients with AML compa...
ORGANISM(S): Homo sapiens 
2011-12-16 | E-GEOD-27863 | biostudies-arrayexpress
UnknownPediatric Out-of-Hospital Cardiac Arrest Characteristics and Their Association With Survival and Neurobehavioral Outcome.
Not available
S-EPMC5138073 | biostudies-literature
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