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TranscriptomicsTransgenic overexpression of Tcfap2c/AP-2gamma results in liver steatosis
We established a mouse model, in which transcription factor Tcfap2c can be activated in an inducible and reversible manner in somatic tissues, taking advantage of the tetracycline-dependent regulatory system. Induction of the transgene led to robust expression in all tissues (except brain and testis...
ORGANISM(S): Mus musculus 
2011-07-25 | E-GEOD-28692 | biostudies-arrayexpress
TranscriptomicsConversion of murine extraembryonic trophoblast stem cells into induced pluripotent stem cells
Extraembryonic trophoblast stem cells (TSC) can be converted to induced pluripotent stem cells (TSC-iPSCs) by overexpressing Oct4, Sox2, Klf4 and cMyc. TSC lines were derived from mice harboring a doxycycline inducible Oct4 allele and an Oct4-GFP reporter that has been demonstrated to be activated i...
ORGANISM(S): Mus musculus 
2011-02-01 | E-GEOD-25872 | biostudies-arrayexpress
TranscriptomicsDerivation and maintenance of murine trophoblast stem cells under defined conditions
Trophoblast stem (TS) cells are in vitro equivalents to the precursor cells of the placenta. In mice, TS cells can be derived either from polar trophectoderm (TE) of blastocyst outgrowths or from postimplantation extraembryonic ectoderm (ExE), originating from polar TE. Since their first successful ...
ORGANISM(S): Mus musculus 
2014-01-28 | E-GEOD-47719 | biostudies-arrayexpress
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