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TranscriptomicsComparison of the Streptococcus pneumoniae D39 lacR Mutant compared to D39 wild-type
Comparison of the Streptococcus pneumoniae D39 lacR mutant compared to D39 wild type in M17 medium+ 0.5 % (w/v) Glucose (GM17) Two condition design comparison of Wild-type strain including a dye swap
ORGANISM(S): Streptococcus pneumoniae D39 
2014-06-20 | E-GEOD-58183 | biostudies-arrayexpress
TranscriptomicsGalactose Vs Glucose
Comparison of the Streptococcus pneumoniae D39 wild type in M17 medium+ 0.5 % (w/v) Galactose (GaM17) compared to M17 medium+ 0.5 % (w/v) Glucose (GM17) Two condition design comparison of Wild-type strain including a dye swap
ORGANISM(S): Streptococcus pneumoniae D39 
2014-06-20 | E-GEOD-58180 | biostudies-arrayexpress
TranscriptomicsComparison of the Streptococcus pneumoniae D39 lacT Mutant compared to D39 wild-type
Comparison of the Streptococcus pneumoniae D39 lacT mutant compared to D39 wild type in M17 medium+ 0.5 % (w/v) Lactose (LM17) One condition design comparision of two strains including a dye swap
ORGANISM(S): Streptococcus pneumoniae D39 
2014-06-20 | E-GEOD-58182 | biostudies-arrayexpress
TranscriptomicsLactose vs Glucose
Comparison of the Streptococcus pneumoniae D39 wild type in M17 medium+ 0.5 % (w/v) Lactose (LM17) compared to M17 medium+ 0.5 % (w/v) Glucose (GM17) One condition design comparision of two strains including a dye swap
ORGANISM(S): Streptococcus pneumoniae D39 
2014-06-20 | E-GEOD-58181 | biostudies-arrayexpress
TranscriptomicsHigh Ni2+ vs Low Ni2+
By using the transcriptomic approach, we have elucidated the effect of Ni2+ on the global gene expression of S. pneumoniae D39 by identifying several differentially expressed genes/operons in the presence of a high extracellular concentration of Ni2+. The genes belonging to the AdcR regulon (adcRCBA...
ORGANISM(S): Streptococcus pneumoniae D39 
2015-11-20 | E-GEOD-73850 | biostudies-arrayexpress
TranscriptomicsFunctional genome analysis of Bifidobacterium breve UCC2003 reveals a major conserved host-colonization factor
Development of the human gut microbiota commences at birth with bifidobacteria being among the first colonizers of the sterile newborn gastrointestinal tract. To date the genetic basis of bifidobacterial colonization and persistence remains poorly understood. Transcriptomic analysis of the 2,422,684...
ORGANISM(S): Bifidobacterium breve UCC2003 
2011-07-01 | E-GEOD-27491 | biostudies-arrayexpress
TranscriptomicsComparison of the Streptococcus pneumoniae D39 wild-type to the D39 galR mutant [GalM17]
We explored the regulatory mechanism of Leloir pathway genes in Streptococcus pneumoniae D39. Here, we demonstrate that the expression of galKT is galactose dependent. By microarray analysis and quantitative RT-PCR, we further show the role of the transcriptional regulator GalR, present upstream of ...
ORGANISM(S): Streptococcus pneumoniae D39 
2015-10-30 | E-GEOD-74501 | biostudies-arrayexpress
TranscriptomicsComparison of the Streptococcus pneumoniae D39 wild-type to the D39 galR mutant [GM17]
We explored the regulatory mechanism of Leloir pathway genes in Streptococcus pneumoniae D39. Here, we demonstrate that the expression of galKT is galactose dependent. By microarray analysis and quantitative RT-PCR, we further show the role of the transcriptional regulator GalR, present upstream of ...
ORGANISM(S): Streptococcus pneumoniae D39 
2015-10-30 | E-GEOD-74500 | biostudies-arrayexpress
TranscriptomicsCodY of Streptococcus pneumoniae: link between nutritional gene regulation and virulence
CodY is a nutritional regulator mainly involved in amino acid metabolism. It has been extensively studied in Bacillis subtilis and Lactococcus lactis. We investigated the role of CodY in gene regulation and virulence of the human pathogen Streptococcus pneumoniae. We constructed a codY-mutant and ex...
ORGANISM(S): Streptococcus pneumoniae TIGR4 
2010-05-25 | E-GEOD-7350 | biostudies-arrayexpress
TranscriptomicsFucose-mediated transcriptional activation of the fcs operon by FcsR in Streptococcus pneumoniae
In this study, we explore the impact of fucose on the transcriptome of S. pneumoniae D39. The expression of various genes and operons, including the fucose uptake PTS and utilization operon (fcs operon), was altered in the presence of fucose. By means of quantitative RT-PCR and β-galactosidase analy...
ORGANISM(S): Streptococcus pneumoniae D39 
2015-04-23 | E-GEOD-65673 | biostudies-arrayexpress
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