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UnknownMatching queried single-cell open-chromatin profiles to large pools of single-cell transcriptomes and epigenomes for reference supported analysis.
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S-EPMC10069468 | biostudies-literature
TranscriptomicsNcoa3 in mouse embryonic stem cells
This SuperSeries is composed of the following subset Series: GSE37262: A Nuclear Receptor Coactivator is Essential for Esrrb Activity and the Induction and Maintenance of the ES Cell State GSE40192: Global gene expression analysis of Ncoa3 knockdown in mouse embryonic stem cells Refer to individual ...
ORGANISM(S): Mus musculus 
2012-10-02 | E-GEOD-40193 | biostudies-arrayexpress
TranscriptomicsDynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets]
Unraveling complex signaling programs animating developmental lineage-decisions is pivotal to differentiate human pluripotent stem cells (hPSC) into pure populations of desired lineages for regenerative medicine. Developmental signals are strikingly temporally dynamic: BMP and Wnt initially specify ...
ORGANISM(S): Homo sapiens 
2013-11-22 | E-GEOD-52657 | biostudies-arrayexpress
GenomicsZic3 interacts with distant regulatory elements to regulate zebrafish developmental genes
Zic3 regulates early embryonic patterning in vertebrates. Its loss-of-function disrupts gastrulation, left-right patterning, and neurogenesis. We use the zebrafish as a model to study the developmental role of Zic3 in vivo. Using a combination of two genomics approaches – ChIP-seq and microarray, we...
ORGANISM(S): Danio rerio 
2014-02-27 | E-GEOD-41458 | biostudies-arrayexpress
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