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TranscriptomicsLentiviral shRNA library screen to identify growth-related genes in malignant melanoma
Little is known about genes that promote melanoma cell growth and proliferation. siRNAs may be used to address the role of individual genesin these processes. RNAi library screens were used in the past to gain a comprehensive overview of all genes involved in cell growth, proliferation, migration an...
ORGANISM(S): Homo sapiens 
2014-01-24 | E-GEOD-46675 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis from Nd2-mutant and control fibroblasts
Background: Mutations of mitochondrial (mt)DNA cause a variety of human diseases and are also implicated in ageing processes. Results: Primary fibroblasts of the conplastic mouse strain C57BL/6J-mtALR/LTJ with a mutation at position nt4738 resulting in a single nucleotide exchange (leucine to meth...
ORGANISM(S): Mus musculus 
2014-11-22 | E-GEOD-63551 | biostudies-arrayexpress
UnknownChromatin accessibility landscape of pediatric T-lymphoblastic leukemia and human T-cell precursors.
Not available
S-EPMC7507092 | biostudies-literature
TranscriptomicsmiR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy (microRNA)
MicroRNA (miRNA) expression profiling identified miR-638 as one of the most significantly overexpressed miRNAs in metastatic lesions compared with primary melanomas. miR-638 enhanced the tumourigenic properties of melanoma cells in vitro and lung colonization in vivo. mRNA expression profiling of mi...
ORGANISM(S): Homo sapiens 
2014-01-30 | E-GEOD-54492 | biostudies-arrayexpress
UnknownMAP3K7 is recurrently deleted in pediatric T-lymphoblastic leukemia and affects cell proliferation independently of NF-κB.
Not available
S-EPMC6006985 | biostudies-literature
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