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TranscriptomicsRNA-seq of wild-type Salmonella Typhimurium SL1344 in the presence and absence of chlorpromazine or Phe-Arg-Beta-Napthylamide
The aim of this experiment was to determine the changes in transcription caused by inhibition of efflux pumps by the Phe-Arg-Beta-Naptylamide (PABN) and chlorpromazine. Four biological replicates per condition were grown to mid-log phase in MOPS minimal media (OD600) and were exposed to the known ef...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2020-06-01 | E-MTAB-8190 | biostudies-arrayexpress
TranscriptomicsTranscriptomic responses of copepodid sea lice (Lepeophtheirus salmonis) exposed to cypermethrin (Betamax®)
This study investigates transcriptomic responses of Atlantic salmon lice, Lepeophtheirus salmonis exposed to cypermethrin, a commonly used antiparasitic agent used in aquaculture. Copepodid L. salmonis were exposed to cypermethrin (Betamax®) at a concentration of 1.0ppb An in vitro bioassay experim...
ORGANISM(S): Lepeophtheirus salmonis 
2016-08-08 | E-GEOD-76555 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of reversibly switchable transgenic model of Myc-mediated cell tumorigenesis treated with tamoxifen sacrificed after 2, 4, 8, 24 h of treatment (activation cohort) or 2, 4, 6, days after a 21 day tamoxifen treatment regime ended (regression cohort)
Transgenic mice expressing both the MycER and BclXL transgenes under the regulation of an insulin promoter were systemically injected with 4-hydroxytamoxifen to acutely activate MycER. Mice were sacrificed at 2, 4, 8 or 24hrs after injection or at time 0 (untreated control mice). For analysis of the...
ORGANISM(S): Mus musculus 
2007-12-12 | E-GEOD-4356 | biostudies-arrayexpress
TranscriptomicsTranscriptome sequencing and comparative transcriptome analysis of the scleroglucan producer Sclerotium rolfsii
Two S. rolfsii transcriptomes obtained from scleroglucan-producing and scleroglucan-nonproducing conditions were pooled and sequenced using the 454 pyrosequencing technique yielding ~350,000 reads. These could be assembled into 21,937 contigs and 171,833 singletons, for which 6,951 had significant m...
ORGANISM(S): Athelia rolfsii 
2010-05-15 | E-GEOD-21040 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of adult drosophila renal tubule vs whole fly
The experiment was designed to identify genes abundant or enriched in adult Drosophila melanogaster Malpighian (renal) tubule as compared to the whole fly.
ORGANISM(S): Drosophila melanogaster 
2004-06-23 | E-MEXP-127 | biostudies-arrayexpress
ProteomicsAlzheimer's disease proteomics
This project aims to determine how the brain proteome is remodeled in Alzheimer's disease (AD). AD is pathologically characterized by an accumulation of insoluble aggregates composed of Abeta peptides in the brain and is clinically characterized by progressive memory impairment. While the precise pa...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2016-12-19 | MSV000080431 | MassIVE
GenomicsCIDR: Collaborative Study on the Genetics of Alcoholism Case Control Study

This is a case-control study of alcoholism, in which the subjects have been drawn from the Collaborative Study on the Genetics of Alcoholism (COGA), a large, ongoing family-based study that includes subjects from seven sites around the US. COGA has gathered detailed, standardized data on ...

phs000125.v1.p1 | EGA
TranscriptomicsResponses to SARS-CoV-2 variants in hACE2 transgenic mice
hACE2 transgenic mice were infected with the original SARS-CoV-2 strain (B.1) and the Beta (B.1.351) variant. Lung and spleen samples were collected 1 day post infection (DPI), 3 DPI and 5 DPI, and mRNA was sequenced.
ORGANISM(S): Mus musculus 
2023-09-22 | E-MTAB-13308 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of primary isolated unstimulated murine splenic DC1 and DC2 from specific pathogen free (SPF), Germ free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice
The transcriptomes of primary isolated unstimulated murine splenic cDC1 and cDC2 from specific pathogen free (SPF) were compared to cDC1 and cDC2 from Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. Total RNA was prepared from sort-purified cDC1 and cDC2 (for each sample ...
ORGANISM(S): Mus musculus 
2020-03-30 | E-MTAB-8883 | biostudies-arrayexpress
TranscriptomicsIntegrated Genomic Analysis of Relapsed Childhood Acute Lymphoblastic Leukemia reveals therapeutic strategies
This SuperSeries is composed of the following subset Series: GSE28460: Expression data from ALL diagnosis and relapse pediatric acute lymphoblastic leukemia cases GSE28461: Promoter methylation data from ALL diagnosis and relapse pediatric acute lymphoblastic leukemia cases Refer to individual Serie...
ORGANISM(S): Homo sapiens 
2011-09-22 | E-GEOD-28462 | biostudies-arrayexpress
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