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TranscriptomicsTranscription profiling of developmental time series for 10 different mutants with a combination of single and double mutants in 6 genes
We analyzed a developmental time course of ten different mutants with a combination of single and double mutants in 6 genes. The samples were collected at the following time points following starvation: 0, 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22 and 24 hours. Dissimilarities between mutant time cours...
ORGANISM(S): Dictyostelium discoideum 
2005-04-08 | E-TABM-6 | biostudies-arrayexpress
TranscriptomicsAllorecognition, via TgrB1 and TgrC1, mediates the transition from unicellularity to multicellularity in the social amoebae Dictyostelium discoideum
The social amoeba Dictyostelium discoideum integrates into a multicellular organism when individual starving cells aggregate and form a mound. The cells then integrate into defined tissues and develop into a fruiting body that consists of a stalk and spores. Aggregation is initially orchestrated by ...
ORGANISM(S): Dictyostelium discoideum 
2016-04-13 | E-GEOD-68063 | biostudies-arrayexpress
TranscriptomicsBacterial discrimination by Dictyostelid amoebae reveals the complexity of ancient interspecies interactions
Transcriptional profiling of D. discoideum revealed sets of genes whose expression is enriched in amoebae interacting with different species of bacteria, including sets that appear specific to amoebae interacting with Gram(+), or with Gram(-) bacteria. In a genetic screen utilizing the growth of mut...
ORGANISM(S): Dictyostelium discoideum 
2013-05-20 | E-GEOD-46386 | biostudies-arrayexpress
TranscriptomicsTranscriptome conservation of the D. discoideum and D. purpureum developmental programs revealed through RNA-sequencing
Cross species comparison of genomes and transcriptomes is a powerful tool for understanding underlying biological processes, accurate functional classification of genes, and discovery of novel elements. The shift to next-generation sequencing platforms has tremendously accelerated the analysis of ge...
ORGANISM(S): Dictyostelium purpureum 
2010-03-12 | E-GEOD-17637 | biostudies-arrayexpress
Transcriptomicsabc transporters in Dictyostelium discoideum development
ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins. ABC transporters are known for the role they play in resistance towards anticancer agents in chemotherapy of cancer patients. There are 68 ABC tran...
ORGANISM(S): Dictyostelium discoideum AX4 
2013-06-14 | E-GEOD-45555 | biostudies-arrayexpress
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