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UnknownStructures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
Not available
S-EPMC5241723 | biostudies-literature
TranscriptomicsThe Anterior Gradient Homolog 3 (AGR3) Gene Is Associated with Differentiation and Survival in Ovarian Cancer
Low-grade serous ovarian carcinoma is believed to arise from serous borderline ovarian tumors, yet the progression from serous borderline tumors to low-grade serous ovarian carcinoma remains poorly understood. The purpose of this study was to identify differentially expressed genes between the two g...
ORGANISM(S): Homo sapiens 
2011-03-04 | E-GEOD-27651 | biostudies-arrayexpress
UnknownElicitation of structure-specific antibodies by epitope scaffolds.
Not available
S-EPMC2964213 | biostudies-literature
UnknownHeterologous epitope-scaffold prime:boosting immuno-focuses B cell responses to the HIV-1 gp41 2F5 neutralization determinant.
Not available
S-EPMC3027617 | biostudies-literature
ProteomicsPSMF1 variants cause a phenotypic spectrum from early-onset Parkinson’s disease to perinatal lethality and disrupt mitochondrial pathways
Dissecting biopathways unveiled by Mendelian gene discovery has provided critical insights into the pathogenesis of Parkinson’s disease (PD) and neurodegeneration, hence catalyzing the identification of potential biomarkers and therapeutic targets. Here, we identify PSMF1 as a new gene implicated in...
ORGANISM(S): Homo sapiens (Human) 
2026-03-03 | PXD053147 | Pride
Parkinson's disease Psmf1 Neurodegeneration 
TranscriptomicsDown-regulation of PAX2 affects ovarian cancer cell growth and migration
PAX2 is one of nine PAX genes that regulate tissue development and cellular differentiation in embryos. PAX2 promotes cell proliferation, oncogenic transformation, cell lineage specification, migration, and survival. In our previous study, we found that PAX2 is highly expressed in low-grade ovarian ...
ORGANISM(S): Homo sapiens 
2011-12-05 | E-GEOD-30501 | biostudies-arrayexpress
TranscriptomicsRole of Humoral Immunity against Hepatitis B Virus Core Antigen in the Pathogenesis of Acute Liver Failure
To investigate the role of viral and host factors in acute liver failure, we analyzed serum and multiple liver specimens obtained at the time of liver transplantation from four well-characterized patients. We carried out an integrated clinicopathological analysis, gene and microRNA expression profil...
ORGANISM(S): Homo sapiens 
2018-10-29 | E-GEOD-96851 | biostudies-arrayexpress
UnknownCombinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein.
Not available
S-EPMC2625307 | biostudies-literature
UnknownSecukinumab in Pediatric Patients with Plaque Psoriasis: Pooled Safety Analysis from Two Phase 3 Randomized Clinical Trials.
Not available
S-EPMC10460311 | biostudies-literature
UnknownGenetic analysis and natural history of Parkinson's disease due to the LRRK2 G2019S variant.
Not available
S-EPMC11146432 | biostudies-literature
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