Sort   by:  
 Page size 
UnknownProtocol for a pragmatic cluster randomised controlled trial assessing the clinical effectiveness and cost-effectiveness of Electronic RIsk-assessment for CAncer for patients in general practice (ERICA).
Not available
S-EPMC10030284 | biostudies-literature
TranscriptomicsMacrophage-Expressed Perforins Mpeg1 and Mpeg1.2 Have an Anti-Bacterial Function in Zebrafish
Macrophage expressed gene 1 (MPEG1) encodes an evolutionary conserved protein with a predicted Membrane Attack Complex/Perforin domain associated with host defence against invading pathogens. In vertebrates, MPEG1 is an integral membrane protein of macrophages, but how it contributes to the macropha...
ORGANISM(S): Danio rerio 
2014-09-01 | E-GEOD-54885 | biostudies-arrayexpress
TranscriptomicsMerck Ad5/HIV induces broad innate immune activation that predicts CD8+ T-cell responses but is attenuated by preexisting Ad5 immunity.
This SuperSeries is composed of the following subset Series: GSE22768: Systems analysis of the Merck Ad5/HIV vaccine reveals robust induction of a core innate immune gene network: in vivo analysis GSE22769: Systems analysis of the Merck Ad5/HIV vaccine reveals robust induction of a core innate immun...
ORGANISM(S): Homo sapiens 
2012-11-20 | E-GEOD-22822 | biostudies-arrayexpress
TranscriptomicsSystems analysis of the Merck Ad5/HIV vaccine reveals robust induction of a core innate immune gene network: in vivo analysis
Here we applied a systems approach to define human innate immune signatures following MRKAd5/HIV immunization and to analyze the effects of pre-existing Ad5 immunity. We defined the global early immune response to MRKAd5/HIV by profiling the PBMC transcriptomes from seven Ad5Neg individuals pre- and...
ORGANISM(S): Homo sapiens 
2012-11-20 | E-GEOD-22768 | biostudies-arrayexpress
TranscriptomicsSystems analysis of the Merck Ad5/HIV vaccine reveals robust induction of a core innate immune gene network: in vitro analysis
Here we applied a systems approach to define human innate immune signatures following MRKAd5/HIV immunization and to analyze the effects of pre-existing Ad5 immunity. To determine whether vaccine-induced changes could be ascribed to cell-intrinsic responses rather than cell population fluxes, fresh ...
ORGANISM(S): Homo sapiens 
2012-11-20 | E-GEOD-22769 | biostudies-arrayexpress
TranscriptomicsMacrophage-specific gene functions in Spi1-directed innate immunity
The Spi1/ Pu.1 transcription factor plays a crucial role in myeloid cell development across many species. Several Spi1 target genes have been identified so far, yet the Spi1-dependent gene group remains largely unknown. To identify novel genes downstream of Spi1 we employed a microarray strategy usi...
ORGANISM(S): Danio rerio 
2010-04-30 | E-GEOD-19206 | biostudies-arrayexpress
TranscriptomicsIsraeli acute paralysis virus – what we have learned about the virus since mysterious disappearance of the US honey bees known as Colony Collapse Disorder (CCD) in 2006
There were important gaps in our knowledge of Israeli acute paralysis virus (IAPV), when IAPV was tightly linked to bee Colony Collapse Disorder (CCD), the mysterious disease that, starting in 2006-2007, has been wiping out honey bees in the US. To fill in these gaps we studied the molecular basis ...
ORGANISM(S): Apis mellifera 
2014-04-08 | E-GEOD-46278 | biostudies-arrayexpress
Sort   by:  
 Page size