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MetabolomicsLactobacillus plantarum MR1 alleviates high-carbohydrate diet-induced oxidative stress and liver lipid deposition via upregulating uridine synthesis
The overconsumption of carbohydrates induces oxidative stress and lipid accumulation in the liver, which can be alleviated by modulation of intestinal microbiota; however, the underlying mechanism remains unclear. Here, we demonstrated that a strain affiliated with Lactobacillus plantarum (de...
2024-01-16 | MTBLS4262 | MetaboLights
MetabolomicsCelery (Apium graveolens L.) Juice Fermented with Lactiplantibacillus plantarum NCU116 Mitigates Type 2 Diabetes in Mice: Mechanistic Insights from Gut Microbiota and Metabolomics

This study aimed to investigate the metabolic effects of fermented celery juice (FCJ) and non-fermented celery juice (NFCJ) in a mouse model of type 2 diabetes. Fresh celery juice was fermented with Lactiplantibacillus plantarum NCU116 under controlled conditions. Male C57BL/6J mice were divided ...

2025-08-06 | MTBLS12826 | MetaboLights
MetabolomicsLactiplantibacillus plantarum HB: A koumiss-derived Lactobacillus alleviates Toxoplasma gondii infection through regulating gut microbiota and metabolism

Toxoplasma gondii (T. gondii) is an obligate intracellular protozoan parasite capable of infecting nearly all warm-blooded animals, including humans, with epidemiological studies indicating remarkably high global infection. However, due to its complex life cycle, no effective vaccine has bee...

2025-09-12 | MTBLS12987 | MetaboLights
TranscriptomicsTranscription profiling of human intestinal mucosa after exposure to Lactobacillus plantarum WCFS1
the human in vivo transcriptional response of small intestinal mucosa to Lactobacillus plantarum
ORGANISM(S): Homo sapiens 
2008-10-17 | E-MEXP-1328 | biostudies-arrayexpress
ProteomicsLactiplantibacillus plantarum cell free supernatant
The proteomic approach provided new insights into the mechanisms of action of L. plantarum CFS.
ORGANISM(S): Lactobacillus plantarum 
2026-06-30 | PXD064835 | Pride
L. plantarum Cfs 
MetabolomicsLactiplantibacillus plantarum PS128 restores microbiota-driven polyamine homeostasis to alleviate autism-like behaviors in Fmr1 knockout mice

Background: Autism spectrum disorder (ASD) is biologically heterogeneous and has limited mechanism-informed interventions targeting core behavioral symptoms. Emerging evidence suggests that gut microbial metabolism shapes neurobehavioral outcomes, yet the specific metabolic pathw...

2026-02-10 | MTBLS13881 | MetaboLights
ProteomicsLactiplantibacillus plantarum as a novel platform for production and purification of integral membrane proteins using RseP as the benchmark
Identification of gel bands from purified fractions from expression of RseP in E.coli and Lactiplantibacillus plantarum.
ORGANISM(S): Lactiplantibacillus Plantarum Escherichia Coli (ncbitaxon:562) 
2023-06-02 | MSV000092087 | MassIVE
TranscriptomicsTranscriptional profile Lactobacillus plantarum WCFS1 : p-coumaric acid (p-CA) treated cells
Whole genome transcriptional profiling was used to characterize the response of Lactobacillus plantarum WCFS1 human isolate during challenge with p-coumaric acid (p-CA). Twelve independent experiments were performed and mixed at random in groups of four for total of three RNA samples. The transcript...
ORGANISM(S): Lactobacillus plantarum 
2013-01-16 | E-GEOD-40126 | biostudies-arrayexpress
MetabolomicsLactiplantibacillus plantarum PS128 restores microbiota-driven polyamine homeostasis to alleviate autism-like behaviors in Fmr1 knockout mice

Background Autism spectrum disorder (ASD) is biologically heterogeneous and has limited mechanism-informed interventions targeting core behavioral symptoms. Emerging evidence suggests that gut microbial metabolism shapes neurobehavioral outcomes, yet the specific metabolic pathwa...

2026-02-06 | MTBLS13859 | MetaboLights
MetabolomicsAlleviation of Loperamide-Induced Constipation by Lactiplantibacillus plantarum SYS1: Role of Properistaltic Metabolites and Promotion of Enteric Nerve Development via 5-HT4R Activation

Background: Constipation is a common gastrointestinal disorder. Lactobacillus plantarum has been reported to have the effect of relieving constipation, but its underlying mechanism remains unclear.

Results: Lactiplantibacillus plantarum SYS1 was identified through in ...

2025-08-06 | MTBLS12821 | MetaboLights
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