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Little is known about the genes involved in the initial cyst formation and disease progression in autosomal dominant polycystic kidney disease (ADPKD). To uncover the genetic determinants and molecular mechanisms of ADPKD, we analyzed 4-point time-series DNA microarrays from Pkd1L3/L3 mice to genera...
ORGANISM(S): Mus musculus 
Parasitic infections with the hookworms Ancylostoma ceylanicum and Necator americanus are a significant global health burden and current hookworm infection management approaches are limited by modest drug efficacy, costs, risk of reinfection and drug resistance. Subunit vaccines based on proteins ex...
ORGANISM(S): Ancylostoma ceylanicum Necator americanus 
2024-12-19 | PXD049200 | Pride
To identify genes differentially expressed during L3 lethargus, we collected RNA during the third larval stage (L3) lethargus period, 37 hours after feeding developmentally-arrested L1 animals. Animals in lethargus were identified based on quiescence of locomotion and feeding. Additional time point...
ORGANISM(S): Caenorhabditis elegans 
We used microarrays to explore the global affect on gene expression in C. elegans after exposure to arsenic L3 stage N2 worms were incubated for 6 hrs in sodium arsenite containing media of concentrations .003 and .03. Three independent extractions of RNA were performed from no exposure, .003 exposu...
ORGANISM(S): Caenorhabditis elegans 
RNA-seq of Drosophila melanogaster wing imaginal discs during L3 stage
The goal of this experiment was to examine the innate immune response to helminth infection in the lung. Hookworms (like many other helminths) use an obligate migration pathway through the lung. Their infection has been characterized in the gut in detail, but early immune responses in the lung have ...
ORGANISM(S): Mus musculus 
modENCODE_submission_659 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commerically available genome til...
ORGANISM(S): Caenorhabditis elegans 
modENCODE_submission_2454 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commerically available genome ti...
ORGANISM(S): Caenorhabditis elegans 
The aim of the present study was to determine the effects of glucuronides of oleanolic acid (GlcUAOA) extracted from Calendula officinalis flower on the profile of immunogenic proteins of somatic extract of infective H. polygyrus bakeri L3 stage.
ORGANISM(S): Heligmosomoides polygyrus bakeri 
2021-04-08 | PXD024205 | Pride
modENCODE_submission_655 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commerically available genome til...
ORGANISM(S): Caenorhabditis elegans 
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