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GenomicsActivity-Induced Regulation of Synaptic Strength through the Chromatin Reader L3mbtl1
Activity-Induced Regulation of Synaptic Strength through the Chromatin Reader L3mbtl1
PRJNA413882 | ENA
TranscriptomicsActivity-Induced Regulation of Synaptic Strength through the Chromatin Reader L3mbtl1
Homeostatic synaptic downscaling reduces neuronal excitability by modulating the number of postsynaptic receptors. Histone modifications and the subsequent chromatin remodeling play critical roles in activity-dependent gene expression. Histone modification codes are recognized by chromatin readers t...
ORGANISM(S): Mus musculus 
2018-06-12 | GSE104802 | GEO
UnknownL3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control.
Not available
S-EPMC6588399 | biostudies-literature
UnknownActivity-Induced Regulation of Synaptic Strength through the Chromatin Reader L3mbtl1.
Not available
S-EPMC6309677 | biostudies-literature
TranscriptomicsThe Polycomb group protein L3MBTL1 represses a SMAD5-mediated transcriptional program in human pluripotent stem cells
Epigenetic regulation of key transcriptional programs is a critical mechanism that controls hematopoietic development and thus aberrant expression patterns or mutations in epigenetic regulators occur frequently in hematologic malignancies. We demonstrate that the Polycomb protein L3MBTL1, which is m...
ORGANISM(S): Homo sapiens 
2017-02-09 | GSE65438 | GEO
UnknownHistone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1.
Not available
S-EPMC2742506 | biostudies-literature
UnknownL3MBTL1 deficiency directs the differentiation of human embryonic stem cells toward trophectoderm.
Not available
S-EPMC3202892 | biostudies-literature
UnknownThe MBT repeats of L3MBTL1 link SET8-mediated p53 methylation at lysine 382 to target gene repression.
Not available
S-EPMC2988377 | biostudies-literature
UnknownL3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability.
Not available
S-EPMC3012470 | biostudies-literature
UnknownDepletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q- polycythemia vera.
Not available
S-EPMC2974589 | biostudies-literature
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