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TranscriptomicsMouse Soleus Muscle Chronic Electrical Stimulation Study
Stimulation of the mouse hindlimb via the sciatic nerve was used to induce contractions for 4 hours to investigate acute muscle gene activation in a model of muscle phenotype conversion. Initial force production (1.6 + 0.1 g/g body weight) declined 45% within 10 min and was maintained for the remain...
ORGANISM(S): Mus musculus 
2010-06-01 | E-GEOD-14391 | biostudies-arrayexpress
UnknownA MicroRNA Cluster miR-23-24-27 Is Upregulated by Aldosterone in the Distal Kidney Nephron Where it Alters Sodium Transport.
Not available
S-EPMC5426511 | biostudies-literature
TranscriptomicsIdentification of differentially expressed genes in fibroblasts derived from patients with Dupuytren's Contracture
Dupuytren's contracture (DC) is the most common inherited connective tissue disease of humans and is hypothesized to be associated with aberrant wound healing of the palmar fascia. Fibroblasts and myofibroblasts are believed to play an important role in the genesis of DC and the fibroproliferation a...
ORGANISM(S): Homo sapiens 
2010-04-16 | E-GEOD-21221 | biostudies-arrayexpress
TranscriptomicsMicroarray study to understand acquired resistance to EGFR-targeted therapy in lung cancer
Activating mutations of EGFR have been characterized as important mechanisms for carcinogenesis in a subset of EGFR-dependent non-small cell lung cancers (NSCLC). EGFR tyrosine kinase inhibitors (TKI), such as erlotinib and gefitinib, have dramatic clinical effects on EGFR-addicted lung cancers and ...
ORGANISM(S): Homo sapiens 
2012-05-29 | E-GEOD-38310 | biostudies-arrayexpress
UnknownEnhanced immune activation within the tumor microenvironment and circulation of female high-risk melanoma patients and improved survival with adjuvant CTLA4 blockade compared to males.
Not available
S-EPMC9164320 | biostudies-literature
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