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ProteomicsRat Serum Exosome LC-MSMS(Label free)
LC-MSMS (Label free) was performed to find differential proteins in maternal rat serum exosome between 3 normal pregnant rats and 3 pregnant rats carrying fetuses with spina bifida aperta induced by all-trans retinoic acid (Sigma; 4% [wt/vol] in olive oil; 140 mg/kg body weight by gavage) at pregnan...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-10-14 | PXD023775 | Pride
Serum exosome Lc-msms Label free Rat 
ProteomicsReproducibility of label-free single-shot phosphoproteomics applied to CRC cell lines
There is a need for robust phosphopeptide enrichment methods to allow signaling network analysis in cancer cell lines and tissues with minimal fractionation. With recent instrument developments thousands of unique phosphopeptides can be detected by single-shot LC-MS/MS. However, successful phosphopr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080715 | MassIVE
ProteomicsComparison of Lung Cancer Proteome Profiles 1: Label Free Quantification
The goal of this project is to compare label free quantification, chemical labeling with tandem mass tags, and data independent acquisition discovery proteomics approaches using lung squamous cell carcinomas and adjacent lung tissues.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-27 | MSV000080685 | MassIVE
OtherIs label-free LC-MS/MS ready for biomarker discovery?
Data from ProteomeXchange, PXD ID: PXD002037. Experiment: 01, file: folder summary. Published as part of Proteomics Clin Appl. 2015 Feb 5 .
ORGANISM(S): Streptococcus_pyogenes_m1_gas, Streptococcus_pyogenes_manfredo 
GPM11210037526 | GPMDB
Resource Reanalysis 
ProteomicsUPS2 Orbitrap data from Dicker, Lin and Ivanov (PMID: 20823122)
These raw data were first introduced in "Increased Power for the Analysis of Label-free LC-MS/MS Proteomics Data by Combining Spectral Counts and Peptide Peak Attributes" by Lee Dicker, Xihong Lin, and Alexander R. Ivanov (PubMed ID 20823122) (doi 10.1074/mcp.M110.002774). They represent the Sigma ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-01-10 | MSV000078520 | MassIVE
ProteomicsHuman hippocampus LC-MSMS
Large-scale analysis of post-translational modification in the hippocampus of patients with Alzheimer's disease using pI shift and label free quantification without enrichment.
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD000950 | Pride
Human brain hippocampus lc-msms 
ProteomicsLabel-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line
Hepatitis B virus (HBV) infection is a major health problem worldwide. Recent evidence suggests that various viruses can manipulate the infection process by secretion of specific viral and cellular components into exosomes, small nanometer-sized (30-150 nm) vesicles secreted from various cells. Howe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080718 | MassIVE
ProteomicsLabel-free quantification of proteins by LC-MS/MS analysis
The P1 and P2 fractions were subjected to label-free proteomics analysis.
ORGANISM(S): Homo Sapiens (human) 
2020-11-13 | PXD016259 | JPOST Repository
OtherFeasibility of label-free phosphoproteomics and application to base-line signaling of colorectal cancer cell lines.
Data from ProteomeXchange, PXD ID: PXD001550. File: QE2_130117_OPL1013_TiOx_CRC_DLD1_3_130125023714.mzml. Published as part of J Proteomics. 2015 Apr 1. pii: S1874-3919(15)00103-7 . From the Abstract: {{i}} Robust phosphopeptide enrichment methods with minimal fractionation are required to profile ...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320014765 | GPMDB
Resource Reanalysis 
ProteomicsLabel-free quantitative phosphoproteomics of ΔB-Raf:ER cells treated with U0126 or 4-HT
ΔB-Raf:ER cells were treated with 10 µM U0126 or 1 µM 4-HT for 30 min. The cells were lysed in 6 M guanidine-HCl containing 100 mM HEPES-NaOH (pH7.5), 10 mM TCEP, and 40 mM CAA. The lysates were dissolved by heating and sonication and then centrifuged. The supernatants were recovered, and proteins (...
ORGANISM(S): Mus Musculus (mouse) 
2022-03-03 | PXD028723 | JPOST Repository
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