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TranscriptomicsComparative genomic hybridization by array of 121 paired tumor and non-tumor tissue samples from patients with non-small cell lung carcinoma to gain a systems biology insight into the current clinical classification
Non-small cell lung cancer (NSCLC), a leading cause of cancer deaths, represents a heterogeneous group of neoplasms, mostly comprising squamous cell carcinoma (SCC), adenocarcinoma (AC) and large-cell carcinoma (LCC). The aim of this study was to gain a systems biology insight into the current clini...
ORGANISM(S): Homo sapiens 
2013-12-11 | E-MTAB-1133 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array on 123 paired tumor and non-tumor tissue samples from patients with non-small cell lung carcinoma to gain a systems biology insight into the current clinical classification
Non-small cell lung cancer (NSCLC), a leading cause of cancer deaths, represents a heterogeneous group of neoplasms, mostly comprising squamous cell carcinoma (SCC), adenocarcinoma (AC) and large-cell carcinoma (LCC). The aim of this study was to gain a systems biology insight into the current clini...
ORGANISM(S): Homo sapiens 
2013-12-11 | E-MTAB-1132 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling by array on 123 paired tumor and non-tumor tissue samples from patients with non-small cell lung carcinoma to gain a systems biology insight into the current clinical classification
Non-small cell lung cancer (NSCLC), a leading cause of cancer deaths, represents a heterogeneous group of neoplasms, mostly comprising squamous cell carcinoma (Squamous cell carcinoma), aC (AC) and large-cell carcinoma (Large cell carcinoma). The aim of this study was to gain a systems biology insig...
ORGANISM(S): Homo sapiens 
2013-12-11 | E-MTAB-1134 | biostudies-arrayexpress
TranscriptomicsIGR_HYPOXIA _MIR210_STUDY_SC
Hypoxia in the tumor microenvironment plays a crucial role in the evasion of immune surveillance by tumor cells. In this study, we aimed to identify the miRs regulated by hypoxia in NSCLC and melanoma and their putative involvement in the regulation of tumor susceptibility to antigen-specific cytoto...
ORGANISM(S): Homo sapiens 
2012-11-01 | E-MTAB-1157 | biostudies-arrayexpress
GenomicsEGAS00001002091 - samples
Using sequencing and gene expression analyses, we identified a subgroup of HCA characterized by fusion of the INHBE and GLI1 genes and activation of sonic hedgehog pathway. Molecular subtypes of HCAs associated with different patients’ risk factors for HCA, disease progression, and pathology feature...
EGAD00001003092 | EGA
GenomicsA new subgroup of hepatocellular adenomas with sonic hedgehog pathway activation
Hepatocellular adenomas (HCA) are benign liver tumors divided in molecular subtypes characterized by mutations inactivating HNF1A, activating β-catenin or the IL-6/JAK/STAT inflammatory pathway. Molecular analyses of 533 HCA developed in 411 patients identified a new tumor subgroup with Sonic Hedgeh...
EGAS00001002091 | EGA
TranscriptomicsTranscription profiling of human T cell lines isolated from tumor infiltrating lymphocytes or peripheral blood lymphocytes of a patient with large cell carcinoma of the lung
The IGR-Heu tumor cell line was established from patient Heu suffering from large cell carcinoma of the lung. Heu171, Heu127 and Heu161 T cell clones were isolated from autologous tumor infiltrating lymphocytes. H32 T cell line and H32-22 clone were isolated from autologous PBL after stimulation wit...
ORGANISM(S): Homo sapiens 
2007-03-02 | E-TABM-208 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lung large cell carncinoma cells grown under hypoxic conditions and treated with STAT3 siRNA
Hypoxia-mediated inhibition of specific tumour cell lysis
ORGANISM(S): Homo sapiens 
2009-03-12 | E-TABM-611 | biostudies-arrayexpress
Unknown<i>PFMG2025</i>-integrating genomic medicine into the national healthcare system in France.
Not available
S-EPMC11910791 | biostudies-literature
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