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MetabolomicsLipid profile analysis of donkey milk during the lactation

Background: From ancient times, donkey milk (DM) has attracted much attention due to its particular properties. Donkey milk is characterized by a high level of lactose and low levels of protein and fat. However, studies investigating lipid changes in donkey milk during lactation are limited....

2025-09-06 | MTBLS12948 | MetaboLights
ProteomicsA Comparative Proteomic Analysis of Whey Protein from Early, Mid and Late Lactation Stages of Indian Indigenous Breed, MalnadGidda (Bosindicus)
Different lactation stages have marked influence on milk yield, milk constituents and nourishment of the neonates. However, the differential gene expression during different lactation stages in Bosindicus has not been investigated so far. In this study, we carried out high-resolution mass spectromet...
ORGANISM(S): Bos indicus 
2018-02-16 | PXD007655 | Pride
Ultracentrifugation Tmt labeling Isoelectric precipitation Brplc Biomarker 
ProteomicsDeciphering the role of MFGE8 in lactation biology using CRISPR-CAS9 based gene editing in Buffalo mammary epithelial cells
Milk fat globule EGF factor 8 (MFGE8) is a glycoprotein which plays a crucial role in mammary gland remodeling. Our group previously identified MFGE8 as a marker associated with high milk yielding cows. Here, we generated MFGE8 knock-out buffalo mammary epithelial cells (BuMEC) via CRISPR-cas9 techn...
ORGANISM(S): Bos taurus (Bovine) 
2025-08-25 | PXD048149 | Pride
Crispr-cas9 Lactation biology Mfge8 
TranscriptomicsCharacterisation of microRNA expression in post-natal mouse mammary gland development [gene]
Background: The differential expression pattern of microRNAs (miRNAs) during mammary gland development might provide insights into their role in regulating the homeostasis of the breast epithelium. Our aim was to analyse these regulatory functions by deriving a comprehensive tissue-specific combined...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-15054 | biostudies-arrayexpress
TranscriptomicsCharacterisation of microRNA expression in post-natal mouse mammary gland development
Background: The differential expression pattern of microRNAs (miRNAs) during mammary gland development might provide insights into their role in regulating the homeostasis of the breast epithelium. Our aim was to analyse these regulatory functions by deriving a comprehensive tissue-specific combined...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-15057 | biostudies-arrayexpress
TranscriptomicsCharacterisation of microRNA expression in post-natal mouse mammary gland development [miRNA]
Background: The differential expression pattern of microRNAs (miRNAs) during mammary gland development might provide insights into their role in regulating the homeostasis of the breast epithelium. Our aim was to analyse these regulatory functions by deriving a comprehensive tissue-specific combined...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-15055 | biostudies-arrayexpress
TranscriptomicsmRNA Expression Comparison Between Igfbp7-null and wild type mice at Lactation Day 3
Insulin like growth factor binding protein 7, Igfbp7, is a secreted protein that in addition to modulating insulin and insulin-like growth factor signaling, it acts as a tumor suppressor gene in breast and other cancers. To elucidate the role of Igfbp7 in regulating the proliferation and differentia...
ORGANISM(S): Mus musculus 
2014-09-02 | E-GEOD-45118 | biostudies-arrayexpress
TranscriptomicsDifferential expression analysis of miRNAs in goat (Capra hircus) mammary gland between peak and late lactation by Solexa sequencing
We report the application of Solexa high-throuthput sequencing technology for miRNA differential expression profiles. Using an optimized data analysis workflow, we mapped about 30 million sequence reads per sample to Ovis aries genome. The results were validated by qRT-PCR. Our study represents t...
ORGANISM(S): Capra hircus 
2013-01-01 | E-GEOD-39484 | biostudies-arrayexpress
ProteomicsCharacterization of Bovine Dry Secretions and their Proteome from the End of Lactation Through Day 21 of the Dry Period
The dry period in cow are critical to mammary health and the success of the next lactation. The expression of proteins the dry period progresses need to be characterized to provide information on involution and immune functions during the dry period. Total protein and lactoferrin concentrations ros...
ORGANISM(S): Bos taurus (Bovine) 
2020-05-20 | PXD017837 | Pride
Mastitis Mammary involution Proteome Dairy cow dry period Bovine dry secretions 
GenomicsA long-lasting prolactin to combat lactation insufficiency
A long-lasting prolactin to combat lactation insufficiency
PRJNA1126103 | ENA
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