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MetabolomicsLactobacillus plantarum MR1 alleviates high-carbohydrate diet-induced oxidative stress and liver lipid deposition via upregulating uridine synthesis
The overconsumption of carbohydrates induces oxidative stress and lipid accumulation in the liver, which can be alleviated by modulation of intestinal microbiota; however, the underlying mechanism remains unclear. Here, we demonstrated that a strain affiliated with Lactobacillus plantarum (de...
2024-01-16 | MTBLS4262 | MetaboLights
TranscriptomicsTranscription profiling of human intestinal mucosa after exposure to Lactobacillus plantarum WCFS1
the human in vivo transcriptional response of small intestinal mucosa to Lactobacillus plantarum
ORGANISM(S): Homo sapiens 
2008-10-17 | E-MEXP-1328 | biostudies-arrayexpress
MetabolomicsLactiplantibacillus plantarum HB: A koumiss-derived Lactobacillus alleviates Toxoplasma gondii infection through regulating gut microbiota and metabolism

Toxoplasma gondii (T. gondii) is an obligate intracellular protozoan parasite capable of infecting nearly all warm-blooded animals, including humans, with epidemiological studies indicating remarkably high global infection. However, due to its complex life cycle, no effective vaccine has bee...

2025-09-12 | MTBLS12987 | MetaboLights
TranscriptomicsTranscriptional profile Lactobacillus plantarum WCFS1 : p-coumaric acid (p-CA) treated cells
Whole genome transcriptional profiling was used to characterize the response of Lactobacillus plantarum WCFS1 human isolate during challenge with p-coumaric acid (p-CA). Twelve independent experiments were performed and mixed at random in groups of four for total of three RNA samples. The transcript...
ORGANISM(S): Lactobacillus plantarum 
2013-01-16 | E-GEOD-40126 | biostudies-arrayexpress
TranscriptomicsImprovement of Lactobacillus plantarum Aerobic Growth by Comprehensive Transcriptome Analysis
An aerobic Lactobacillus plantarum culture displayed growth stagnation during early growth. Transcriptome analysis revealed that regain of growth after stagnation correlated with activation of CO2-producing pathways suggesting that limiting CO2-concentration induced stagnation. Analogously providing...
ORGANISM(S): Lactobacillus plantarum WCFS1 
2010-05-26 | E-GEOD-10194 | biostudies-arrayexpress
TranscriptomicsMucosal responses of healthy humans to exponentially growing or stationary Lactobacillus plantarum bacteria
Some commensal bacteria stimulate the immune system but do not present specific antigenicity. Such adjuvant effects have been reported for the bacterial species Lactobacillus plantarum. To study in vivo human responses to L. plantarum, a randomised double-blind placebo-controlled cross-over study wa...
ORGANISM(S): Homo sapiens 
2009-01-20 | E-GEOD-11355 | biostudies-arrayexpress
TranscriptomicsLactobacillus plantarum IMDO 130201, a wheat sourdough isolate, adapts to growth in wheat sourdough simulation medium at different pH values through differential gene expression
Sourdough is a very competitive and challenging environment for microorganisms. Usually, a stable microbiota composed of lactic acid bacteria (LAB) and yeasts comes to dominate this ecosystem. Although rich in carbohydrates, thus providing an ideal environment to grow, the low pH presents a particul...
ORGANISM(S): Lactobacillus plantarum 
2011-07-31 | E-GEOD-23945 | biostudies-arrayexpress
TranscriptomicsSuppression of virus-induced CCL2, CXCL10 and IL-6: biomarkers of Lactobacillus-mediated protection at the respiratory tract
In this manuscript, we present a more extensive analysis of inflammatory suppression mediated by L. plantarum at the respiratory tract. Via full genome microarray of whole lung tissue, we have generated an extensive list of soluble proinflammatory mediators that are expressed in response to PVM inf...
ORGANISM(S): Mus musculus 
2015-11-02 | E-GEOD-66721 | biostudies-arrayexpress
ProteomicsLipoproteins contribute to the anti-inflammatory capacity of Lactobacillus plantarum WCFS1
This project investigated the role of lipoproteins in immune signaling by the model probiotic Lactobacillus plantarum, by mutagenesis of the prolipoprotein diacylglyceryltransferase encoding lgt gene involved in lipoprotein acylation.
ORGANISM(S): Lactobacillus plantarum WCFS1 
2020-07-13 | PXD019218 | Pride
Lactobacillus plantarum Prolipoprotein diacylglyceryltransferase Lgt Toll-like receptor signaling Host-microbe interactions Lipoproteins 
ProteomicsLactiplantibacillus plantarum as a novel platform for production and purification of integral membrane proteins using RseP as the benchmark
Identification of gel bands from purified fractions from expression of RseP in E.coli and Lactiplantibacillus plantarum.
ORGANISM(S): Lactiplantibacillus Plantarum Escherichia Coli (ncbitaxon:562) 
2023-06-02 | MSV000092087 | MassIVE
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