Upon reaching an OD600 of 0.3, L.
reuteri cultures were treated with 100 µM TCA, HCA, or
TCDCA. For BSHs inhibition assays, additional wells were treated with 100 µM
HCA + GR7. Both negative control and MRS medium control groups were included.
Cultures were terminated at 7...
The mechanisms by which probiotics ameliorate neurodegenerative diseases have garnered significant scientific interest, yet elucidating their underlying pathways remains challenging. In this study, we establish an integrated multi-omics and network pharmacology strategy to unravel the prote...
Abstract
Background
The gut microbiota is a key regulator of host lipid metabolism. In indigenous pigs, variation in growth performance and intramuscular fat (IMF) deposition has been linked to microbiota-host interactions, yet the specific taxa and metabolites that govern host lipid ...