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MetabolomicsMetabolomic profiling reveals the effects of early-life lactoferrin intervention on protein synthesis, energy production and antioxidative capacity in the liver of suckling piglets

The objective of this study was to reveal the effects of early life lactoferrin intervention on the liver metabolism in the suckling piglets. Sixty newborn piglets with an average initial body weight (BW) of 1.51 ± 0.05 kg were assigned to the control (CON) group and the lactoferrin (LF) group. P...

2022-03-01 | MTBLS2279 | MetaboLights
MetabolomicsDietary lactoferrin supplementation enhances immune function, improves intestinal integrity and reshapes gut microbiota in kittens

Background: Lactoferrin is a natural iron-binding glycoprotein with antimicrobial, immunomodulatory and barrier-protective activities, and it is widely applied in human nutritional supplements and infant food additives, but its application potential in pet food remains undetermined. Th...

2026-04-20 | MTBLS13713 | MetaboLights
GenomicsCaco2 response to methotrexate, lactoferrin, and methotrexate-lactoferrin co-exposure
Caco2 response to methotrexate, lactoferrin, and methotrexate-lactoferrin co-exposure
PRJNA588171 | ENA
ProteomicsLactoferrin-Osteopontin Complexes: Insights into Intestinal Organoid Bioavailability and Gut Microbiota Modulation
Lactoferrin (LF) and osteopontin (OPN) are key bioactive milk proteins with significant immune-modulatory, gut, and systemic health benefits. Using a microarrayed high-throughput 3D intestinal organoid platform, we evaluated the bioavailability and uptake of bovine LF-OPN soluble complexes (SC) and ...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2025-07-10 | PXD064048 | Pride
Lactoferrin Osteopontin Human Bovine 
GenomicsEffect of lactoferrin treatment on iAEC2
Effect of lactoferrin treatment on iAEC2
PRJNA719377 | ENA
ProteomicsSite-specific glycosylation of donkey milk lactoferrin investigated by High Resolution Mass Spectrometry
A comprehensive glycosylation profile of donkey lactoferrin, isolated by ion exchange chromatography from an individual milk sample, was obtained by means of chymotryptic digestion, TiO2 and HILIC enrichment, reversed-phase high performance liquid chromatography, electrospray mass spectrometry, and...
ORGANISM(S): Equus asinus (Donkey) 
2016-08-25 | PXD004289 | Pride
Lactoferrin glycosylation · donkey milk · n-glycan structures · tio2 and hilic enrichment · mass spectrometry 
ClinicalBovine Lactoferrin in Reducing Taste Disturbances in Patients With Colorectal Cancer Receiving Oxaliplatin-Based Chemotherapy
The purpose of this research study is to determine if using a lactoferrin supplement will improve taste perception. Lactoferrin is a type of protein that is naturally produced in the body and is commonly found in saliva.
2125203 | ecrin-mdr-crc
GenomicsEffects of lactoferrin in PM2.5-induced nephrotoxicity
Effects of lactoferrin in PM2.5-induced nephrotoxicity
PRJNA859375 | ENA
TranscriptomicsEffect of lactoferrin treatment on iAEC2
In an attempt to understand the mode of antiviral action of lactoferrin on SARS-CoV-2 infection, we focused on the effect of lactoferrin on uninfected cells. We decided to use a physiologically relevant cell model of iPSC derived- alveolar epithelial cells (the iAEC2). We specifically focused on ant...
ORGANISM(S): Homo sapiens 
2021-07-15 | GSE171390 | GEO
ProteomicsA 17 kDa fragment of lactoferrin associates with the termination of inflammation and peptides within promote resolution
During the resolution of inflammation macrophages engulf apoptotic polymorphonuclear cells (PMN) and can accumulate large numbers of their corpses. Here we report that resolution-phase-macrophages acquire the neutrophil-derived glycoprotein lactoferrin (Lf) in vivo and ex vivo and process it to shor...
ORGANISM(S): Bos taurus (Bovine) 
2018-03-20 | PXD009190 | Pride
Netosis Lactoferrin Macrophages Efferocytosis Resolution of inflammation 
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