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TranscriptomicsGene expression analysis in mice with heart muscle-specific repression of CELF activity (MHC-CELFdelta)
Members of the CUG-BP, Elav-like family (CELF) regulate alternative splicing in the heart. In MHC-CELFdelta transgenic mice, CELF splicing activity is inhibited postnatally in heart muscle via expression of a nuclear dominant negative CELF protein under an a-myosin heavy chain promoter. MHC-CELFde...
ORGANISM(S): Mus musculus 
2013-08-26 | E-GEOD-40677 | biostudies-arrayexpress
TranscriptomicsAnalysis of cardiac gene expression in juvenile versus mature mice with repressed CELF activity (MHC-CELFdelta)
CUG-BP, Elav-like family (CELF) proteins regulate alternative splicing. In MHC-CELFdelta transgenic mice, CELF-mediated alternative splicing is disrupted in heart muscle via expression of a nuclear dominant negative CELF protein under an alpha-myosin heavy chain promoter. MHC-CELFdelta mice develo...
ORGANISM(S): Mus musculus 
2014-10-16 | E-GEOD-62363 | biostudies-arrayexpress
TranscriptomicsGene Expression in Myotonic Dystrophy
In order to examine the changes in gene expression between normal and myotonic dystrophic animals, gene expression array studies were done with extensor digitorum longus (EDL) of transgenic HSALR line 20b mice using Affymetrix MOE430 2.0 microarrays. We used EDL muscle from transgenic HSALR line 20b...
ORGANISM(S): Mus musculus 
2012-10-21 | E-GEOD-24920 | biostudies-arrayexpress
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