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TranscriptomicsAn oncogenic Kras expression signature identified by cross-species
Mouse lung cancers were generated using the KrasLA model, in which a latent mutated Kras2 allele (resulting in the amino acid substitution G12D) is sporadically activated through spontaneous homologous recombination. These mice develop lung adenomas with full penetrance; over time, the tumors acquir...
ORGANISM(S): Mus musculus 
2013-08-01 | E-GEOD-49200 | biostudies-arrayexpress
TranscriptomicsDNA methylation in postmortem brain samples from autism cases and controls
We used the Illumina 450KMethylation BeadChip to measure DNA methylation at 485,512 loci across the genome for 40 postmortem brain samples. The purpose of our study was to identify differentially methylated regions (DMRs) associated with autism. Samples included 16 temporal cortex brain tissue sampl...
ORGANISM(S): Homo sapiens 
2013-12-12 | E-GEOD-53162 | biostudies-arrayexpress
TranscriptomicsDNA methylation data from non-immortalized lymphocyte samples from participants of the AGES Reykjavik Study
Genome-wide DNA methylation was studied to identify regions with extreme inter-individual variability, half of which show stability within-person, and some of which show covariation with body mass index consistently and are located in or near genes previously implicated in regulating body weight or ...
ORGANISM(S): Homo sapiens 
2010-09-14 | E-GEOD-23858 | biostudies-arrayexpress
UnknownInteraction between Maternal Immune Activation and Antibiotic Use during Pregnancy and Child Risk of Autism Spectrum Disorder.
Not available
S-EPMC7839062 | biostudies-literature
TranscriptomicsDNA methylation data from human iPS cells and fibroblasts
DNA methylation is often inversely correlated with gene expression. We used custom Nimblegen microarrays to determine the relationship between DNA methylation and gene expression in 6 iPS cell lines and the fibroblasts from which they were derived. We isolated genomic DNA from iPS cells and fibrobla...
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-18227 | biostudies-arrayexpress
TranscriptomicsHuman iPS cells and fibroblasts
This SuperSeries is composed of the following subset Series: GSE18226: Expression data from human iPS cells and fibroblasts GSE18227: DNA methylation data from human iPS cells and fibroblasts Refer to individual Series
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-18111 | biostudies-arrayexpress
TranscriptomicsExpression data from human iPS cells and fibroblasts
DNA methylation is often inversely correlated with gene expression. We used expression microarrays to determine the relationship between DNA methylation and gene expression in 6 iPS cell lines and the fibroblasts from which they were derived. We isolated RNA from iPS cells and fibroblasts for which ...
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-18226 | biostudies-arrayexpress
UnknownDifferential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts.
Not available
S-EPMC2958040 | biostudies-literature
UnknownAssociation between acetaminophen metabolites and CYP2E1 DNA methylation level in neonate cord blood in the Boston Birth Cohort.
Not available
S-EPMC10439592 | biostudies-literature
Unknown"Gap hunting" to characterize clustered probe signals in Illumina methylation array data.
Not available
S-EPMC5142147 | biostudies-literature
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