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GenomicsGenome-wide analysis of insulin-like growth factor 1 receptor (IGF1R) binding sites in DFB cells
The insulin-like growth factor 1 receptor (IGF-1R) plays crucial roles in developmental and cancer biology. Most of its biological effects have been ascribed to its tyrosine kinase activity. We report that IGF-1 promotes the modification of IGF-1R by small ubiquitin-like modifier protein-1 (SUMO-1) ...
ORGANISM(S): Homo sapiens 
2010-08-25 | E-GEOD-23792 | biostudies-arrayexpress
TranscriptomicsExpression analysis LPS stimulated THP-1 cells in four paired samples
Macrophages play a critical role in innate immunity, and the expression of early response genes orchestrate much of the initial response of the immune system. Macrophages undergo extensive transcriptional reprogramming in response to inflammatory stimuli such as Lipopolysaccharide (LPS). To identif...
ORGANISM(S): Homo sapiens 
2012-03-07 | E-GEOD-32141 | biostudies-arrayexpress
GenomicsChIP-seq analysis LPS stimulated THP-1 cells
Macrophages play a critical role in innate immunity, and the expression of early response genes orchestrate much of the initial response of the immune system. Macrophages undergo extensive transcriptional reprogramming in response to inflammatory stimuli such as Lipopolysaccharide (LPS). To identif...
ORGANISM(S): Homo sapiens 
2012-03-07 | E-GEOD-32324 | biostudies-arrayexpress
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