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Lactate dehydrogenase 5 (LDH5), an enzyme overexpressed in many cancers, is an attractive target for anticancer therapy. Recently, we successfully designed an LDH5 peptide inhibitor, cGmC9, by targeting protein-protein interactions required for LDH5 enzymatic activity. LDH5 is expressed in the cytos...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-05-06 | PXD029126 | Pride
The AVAglio and RTOG-0825 randomized, placebo-controlled phase III trials in newly diagnosed glioblastoma reported prolonged progression-free survival (PFS), but not overall survival (OS), with the addition of bevacizumab to radiotherapy/temozolomide. To establish whether certain patient subgroups d...
ORGANISM(S): Homo sapiens 
LC-MS/MS analysis of fractionated extracts from Plasmodium falciparum
ORGANISM(S): Plasmodium Falciparum (ncbitaxon:5833) 
2019-06-16 | MSV000083980 | MassIVE
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