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TranscriptomicsTranscription profiling of different types of cells in murine hair follicle to study cell type-specific gene expression.
Hair follicle matrix, outer root sheath, dermal papilla cells and melanocytes and a dermal fraction enriched in fibroblasts were FACS isolated from 4d backskins. Targets from two biological replicates of each were generated and the expression profiles were determined using Affymetrix Mouse Genechip...
ORGANISM(S): Mus musculus 
2007-09-07 | E-GEOD-3142 | biostudies-arrayexpress
TranscriptomicsKey roles for SRF in embryonic epidermal differentiation
During development, a polarized sheet of epidermal cells undergoes stratification and differentiation to produce the skin barrier. Through mechanisms poorly understood, the process involves adhesion and Notch signaling. To elucidate how epidermal embryogenesis is governed, we conditionally targeted ...
ORGANISM(S): Mus musculus 
2011-01-20 | E-GEOD-25548 | biostudies-arrayexpress
TranscriptomicsGene Expression data of P4 stage hair follicle ORS cells from DTG (K14-rtTA,TRE-miR-125b) and control littermates
Increasing evidence suggests that microRNAs may play important roles in regulating self-renewal and differentiation in mammalian stem cells (SCs). Here, we explore this issue in skin. We first characterize microRNA expression profiles of skin SCs versus their committed proliferative progenies and id...
ORGANISM(S): Mus musculus 
2011-01-04 | E-GEOD-26394 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of bulge stem cells
In adult skin, each hair follicle contains a reservoir of stem cells (the bulge), which can be mobilized to regenerate the new follicle with each hair cycle and to reepithelialize epidermis during wound repair. Here we report new methods that permit their clonal analyses and engraftment and demonstr...
ORGANISM(S): Mus musculus 
2012-10-19 | E-GEOD-41704 | biostudies-arrayexpress
TranscriptomicsFrequent occurrence of deletions in primary mediastinal B-cell lymphoma
Primary mediastinal B-cell lymphoma (PMBCL) is a distinct subtype of diffuse large B-cell lymphoma. PMBCL has been previously studied with a variety of genomic techniques resulting in frequent detection of chromosomal gains; however, chromosomal losses have been rarely reported. This finding contr...
ORGANISM(S): Homo sapiens 
2007-08-15 | E-GEOD-7383 | biostudies-arrayexpress
TranscriptomicsExpression data of P4 stage hair follicle early bulge and non-bulge ORS cells
Increasing evidence suggests that microRNAs may play important roles in regulating self-renewal and differentiation in mammalian stem cells (SCs). Here, we explore this issue in skin. We first characterize microRNA expression profiles of skin SCs versus their committed proliferative progenies and id...
ORGANISM(S): Mus musculus 
2011-01-04 | E-GEOD-26393 | biostudies-arrayexpress
GenomicsGenetic and Functional Drivers of Diffuse Large B Cell Lymphoma
Diffuse large B cell lymphoma (DLBCL) is the most common hematologic malignancy and is characterized by a striking degree of heterogeneity. We enrolled a total of 1001 DLBCL patients and comprehensively defined the landscape of genetic mutations, copy number alterations and expression through whole-...
EGAS00001002606 | EGA
Genomicsena-DATASET-DAVELAB-01-09-2017-13:58:58:766-116 - samples
Exome sequencing data for 1001 DLBCL patients and RNA sequencing data for 775 DLBCL patients
EGAD00001003600 | EGA
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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