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MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
UnknownTargeting SPHK1/S1PR3-regulated S-1-P metabolic disorder triggers autophagic cell death in pulmonary lymphangiomyomatosis (LAM).
Not available
S-EPMC9772321 | biostudies-literature
UnknownOverexpression of a LAM domain containing RNA-binding protein LARP1c induces precocious leaf senescence in Arabidopsis.
Not available
S-EPMC3887763 | biostudies-literature
UnknownComparative Transcriptome Profiling Reveals the Genes Involved in Storage Root Expansion in Sweetpotato (Ipomoea batatas (L.) Lam.).
Not available
S-EPMC9321896 | biostudies-literature
ProteomicsComparative proteomic analysis reveals the different hepatotoxic mechanisms of human hepatocytes exposed to silver nanoparticles
Silver nanoparticles (AgNPs), which have been used extensively in consuming products and eventually released into the natural environment, have aroused concerns recently because of their potentially harmful effects on human beings following various routes of exposure. As the liver is one of the larg...
ORGANISM(S): Homo sapiens (Human) 
2022-12-21 | PXD029511 | Pride
Human hepatocytes Silver nanoparticles 
ProteomicsExploring the Cytotoxic Mechanisms and Anticancer Potentials of Silver Nanoparticles in Cisplatin-Sensitive and -Resistant Lung Adenocarcinoma: Insights from Proteomic and Mice Xenograft Studies
Silver nanoparticles (AgNPs) have shown great potential as therapeutic agents due to their ability to cause apoptotic cell death in cancer cells. However, little knowledge is available regarding the underlying action mechanisms of AgNPs towards multi-drug resistant cancer cells. Herein, we employed ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-30 | PXD064272 | Pride
Silver nanoparticles Resistance Proteomics Nsclc Cisplatin 
UnknownTumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion.
Not available
S-EPMC6829598 | biostudies-literature
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
UnknownSynthesis and biological activity evaluation of novel peroxo-bridged derivatives as potential anti-hepatitis B virus agents.
Not available
S-EPMC6072307 | biostudies-literature
UnknownIdentification and functional characterization of a flavonol synthase gene from sweet potato [Ipomoea batatas (L.) Lam.].
Not available
S-EPMC10206235 | biostudies-literature
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