Sort   by:  
 Page size 
TranscriptomicsLAMP2A WT and KO on cell line derived xenografts tumors
The goal of the experiment is to compare the gene expression from LAMP2A-KO xenografts with control tumors.
ORGANISM(S): Homo sapiens 
2025-01-23 | E-MTAB-14665 | biostudies-arrayexpress
ProteomicsTargeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity
Chaperone-mediated autophagy (CMA), a selective autophagic process, plays a crucial role in maintaining intracellular quality and facilitating cellular responses to stress. While CMA has been implicated in finely regulating the stemness of normal stem cells, its significance in cancer stem cells (CS...
ORGANISM(S): Homo sapiens (Human) 
2025-09-22 | PXD060464 | Pride
Mst4 Chaperone-mediated autophagy Gsc Lamp2a Gbm 
GenomicsLAMP2A WT and KO on cell line derived xenografts tumors
LAMP2A WT and KO on cell line derived xenografts tumors
PRJEB83229 | ENA
ProteomicsARPE-19 human cell lines (Small Extracellular Vesicles, early and late endosomes)
LAMP2A affects endosomal biology, including the degradation and exosome pathways. Findings reveal how LAMP2A influences endosomal maturation, protein composition, and communication potential, linking its decline in aging to impaired cellular clearance and tissue homeostasis.
ORGANISM(S): Homo sapiens (Human) 
2026-01-19 | PXD070994 | Pride
Human 
GenomicsRNA-seq analysis of transcriptomes in control and LAMP2A-overexpressed D3 ES cells
RNA-seq analysis of transcriptomes in control and LAMP2A-overexpressed D3 ES cells
PRJNA602736 | ENA
TranscriptomicsRNA-seq analysis of transcriptomes in control and LAMP2A-overexpressed D3 ES cells
The role of autophagy and metabolism in regulating the pluripotency of stem cells is not well understood. LAMP2A is a key gene in CMA. Here we compared transcriptomic changes in LAMP2A-overexpressed D3 versus control cells, as well as changes in LAMP2A-overexpressed cells with versus without DM-αKG ...
ORGANISM(S): Mus musculus 
2020-11-08 | GSE144093 | GEO
ProteomicsLAMP1 and LAMP2 proximity labelling
The aim of the study is to capture the endogenous protein interactomes of LAMP1 and LAMP2A in human neurons using proximity labelling. This was carried out using full-length LAMP1 or LAMP2A fused to the light-activated biotin ligase LOV-Turbo, in cortical neurons differentiated from human iPSCs (I3...
ORGANISM(S): Homo sapiens (Human) 
2026-01-21 | PXD067562 | Pride
Lov-turbo Lamp1 Turboid Lamp2a 
UnknownLAMP2A regulates endosomal protein composition and membrane identity in exosome biogenesis.
Not available
S-EPMC12768870 | biostudies-literature
UnknownTumor cells induce LAMP2a expression in tumor-associated macrophage for cancer progression.
Not available
S-EPMC6413476 | biostudies-literature
UnknownLAMP2A overexpression in breast tumors promotes cancer cell survival via chaperone-mediated autophagy.
Not available
S-EPMC3494593 | biostudies-literature
Sort   by:  
 Page size