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TranscriptomicsTranscription profiling of mouse parental cell line YAMC, plus bleo/Neo vector control, mp53-expressing, Ras-expressing and mp53/Ras cells reveals a synergistic response to oncogenic mutations defines gene class critical to cancer phenotype
Understanding the molecular underpinnings of cancer is of critical importance to developing targeted intervention strategies. Identification of such targets, however, is notoriously difficult and unpredictable. Malignant cell transformation requires the cooperation of a few oncogenic mutations that ...
ORGANISM(S): Mus musculus 
2008-06-18 | E-GEOD-9199 | biostudies-arrayexpress
ProteomicsDeciphering the impact of ectopic SNAI1 expression on renal tubular cell proteome and functions
Snail1 is crucial in regulating epithelial mesenchymal transition (EMT), which leads to excessive extracellular matrix (ECM) production and organ fibrosis including the kidney. Elucidating the roles of snail1 in EMT and kidney fibrosis is thus vital for developing targeted therapies. This study inve...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD061033 | Pride
Renal fibrosis Senescence Proteomics Snail1 Kidney 
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