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TranscriptomicsTranscription profiling of cancer progression to study the intrinsic regulation of transforming growth factor-beta signaling in ErbB2/Neu-induced tumors
To identify early events of erbB2-induced mammary tumorigenesis, we compared datasets from 14 genechip experiments including MMTV-neu tumors, preneoplastic neu mammary gland (adjacent neu), and age-matched, wild-type control mammary glands
ORGANISM(S): Mus musculus 
2007-09-04 | E-GEOD-2528 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of 5- and 10-week bitransgenic mouse mammary glands (LH x MMTV-neu) to identify genes that may facilitate early steps of ErbB2/Neu-mediated mammary tumorigenesis.
To identify genes that may facilitate early steps of ErbB2/Neu-mediated mammary tumorigenesis, we performed comparative microarray analysis of 5- and 10-week bitransgenic mammary glands (LHxMMTV-neu) in triplicate. Experiment Overall Design: We analyzed 3 pooled RNA samples that represented 3 anima...
ORGANISM(S): Mus musculus 
2007-12-01 | E-GEOD-3501 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse mammary tumor-initiating cells
Using a syngeneic p53 null mouse mammary gland tumor model that closely mimics human breast cancer, we have identified by limiting dilution transplantation as well as in vitro mammosphere and clonogenic assays a Lin-CD29HighCD24High subpopulation of tumor-initiating cells. Differentially expressed ...
ORGANISM(S): Mus musculus 
2008-10-18 | E-GEOD-8863 | biostudies-arrayexpress
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