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TranscriptomicsRNA-seq of mouse pancreatic pericytes from wild-type and Tcf7l2-mutated mice
To characterise their gene expression, wild type pancreatic pericytes were isolated based on the YFP-labeling from Nkx3.2-Cre;EYFP mice. As control, whole isolated islets were analysed.To identify Tcf7l2-depenedent genes, pancreatic pericytes were isolated from Nkx3.2-Cre;EYFP;Tcf7l2 flox/flox trans...
ORGANISM(S): Mus musculus 
2017-12-14 | E-MTAB-5325 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mouse embryonic pancreatic mesenchyme
To determine changes in pancreatic mesenchymal cells during embryonic development, we analyzed the transcriptome of these cells at three embryonic days: 13.5 ('L1'), 15.5 ('L2'), and 17.5 ('L3'). Pancreatic mesenchymal cells were isolated by FACS from Nkx3.2-Cre;LSL-YFP pancreatic tissues based on t...
ORGANISM(S): Mus musculus 
2019-01-14 | E-MTAB-7448 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of mouse pancreatic islets from non-transgenic and pericyte MyD88-mutated mice
To elucidate the role of pericytic cytokines in islet inflammation, we interfered with the expression of MyD88, a key modulator of the IL1R1/TLR pathway, in pericytes using transgenic mice (Nkx3.2-Cre;MyD88 flox/flox) . To determine the impact on islet immune cells, we isolated CD45+ cells from the ...
ORGANISM(S): Mus musculus 
2023-12-31 | E-MTAB-13640 | biostudies-arrayexpress
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