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ProteomicsLC7 Proteomic Analysis of Matched Control and NSCLC Lung Adenocarcinoma Tissue.
Non-small cell lung adenocarcinoma is the most frequently diagnosed lung cancer type and remains the leading cause of cancer mortality for men and women in the United States. Management of lung cancer is hindered by high false-positive rates due to the inability to resolve benign versus malignant tu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080825 | MassIVE
ProteomicsDistinct cell type-specific protein signatures in GRN and MAPT genetic subtypes of frontotemporal dementia
INTRODUCTION: Frontotemporal dementia (FTD) is characterized by progressive atrophy of frontal and/or temporal cortices and considerable clinical, pathological, and genetic heterogeneity. METHODS: Frontal and temporal cortex tissues from FTD-GRN (n=9), FTD-MAPT (n=13), and non-demented controls (n=1...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD031419 | Pride
Frontotemporal dementia  grn  mapt  human brain proteomics  cell type enrichment 
ProteomicsGENETIC SUBTYPE- AND CELL TYPE-SPECIFIC PROTEIN SIGNATURES IN FRONTOTEMPORAL DEMENTIA
Frontotemporal dementia is characterized by progressive atrophy of frontal and/or temporal cortices and an early age of onset. The disorder is highly heterogenic, comprising several genetic causes as well as a diverse phenotypic landscape of sporadic cases. Here we investigated the proteomic signatu...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD022872 | Pride
Frontotemporal dementia  c9orf72  grn  mapt  human brain proteomics 
ProteomicsProteomics of the temporal cortex in Semantic Dementia reveals brain-region specific molecular pathology and regulation of the TDP-43-ANXA11 interactome
Semantic dementia (SD) is a clinical subtype of frontotemporal dementia characterized by impaired word comprehension and semantic memory, and occurs nearly always sporadically. Neuroimaging typically reveals asymmetric, predominantly left-sided, atrophy of the anterior temporal pole, anterior fusifo...
ORGANISM(S): Homo sapiens (Human) 
2026-01-16 | PXD062722 | Pride
Semantic dementia  ftld-tdp type c  temporal cortex  quantitative proteomics  rnp complex  presynaptic regulation calcium levels  tardbp-anxa11 interactome  immunohistochemistry 
UnknownChronic kidney disease, cerebral blood flow, and white matter volume in hypertensive adults.
Not available
S-EPMC4818564 | biostudies-literature
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