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Cell cycle dependent transcriptome changes of H. salinarum were analyzed using DNA microarrays. Cells were synchronized by a reversible cell cycle arrest caused by addition of the DNA polymerase inhibitor Aphidicolin. Gene expression of the synchronized cells at different time points after Aphidicol...
ORGANISM(S): Halobacterium salinarum 
In Myxococcus xanthus 55% of the more than 250 two-component signal transduction systems (TCS) genes are orphan. We hypothesized that the histidine kinase SgmT and the response regulator DigR, which comprises a DNA binding domain of the HTH_Xer type, function together to regulate gene expression. We...
ORGANISM(S): Myxococcus xanthus 
Silver nanoparticles cause toxicity in exposed organisms and are an environmental health concern. The mechanisms of silver nanoparticle toxicity, however, remain unclear. We examined the effects of exposure to silver in nano-, bulk- and ionic forms on zebrafish embryos (Danio rerio) using a Next Gen...
ORGANISM(S): Danio rerio 
Krohn2011 - Cerebral amyloid-β proteostasis regulated by membrane transport protein ABCC1 This model is described in the article: Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice. Krohn M, Lange C, Hofrichter J, Scheffler K, Stenze...
2024-09-02 | BIOMD0000000618 | BioModels
This study aimed to investigate the transcriptional differences to metal exposure in two populations of Brown trout. These trout were taken from two separate locations, one population with historic exposure to metals and evidence of metal tolerance, and a second population from a clean environment. ...
ORGANISM(S): Salmo trutta 
Comparison between APPPS1-FVB and APPPS1-FVBxABCC1ko mice Mouse brain expression analysis
ORGANISM(S): Mus musculus 
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