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TranscriptomicsTranscription profiling of human CMV-stimulated CD69+, hCMV-stimulated CD69- and unstimulated monoclonal CD4+ T-LGL lymphocytes from peripheral blood samples from four TCRVbeta+/CD4+ T-LGL lymphocytosis patients
Recent studies suggest the potential involvement of common antigenic stimuli on the ontogeny of monoclonal TCRalphabeta+/CD4+/NKa+/CD8-/+dim T-large granular lymphocyte (LGL) lymphocytosis. Since healthy individuals show (oligo)clonal expansions of hCMV-specific TCRVbeta+/CD4+/cytotoxic/memory T-cel...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-12488 | biostudies-arrayexpress
ProteomicsHigh-throughput proteomics identifies THEMIS2 as independent biomarker of inferior treatment-free survival in untreated chronic lymphocytic leukemia
Notwithstanding advances in the prognostication of chronic lymphocytic leukemia (CLL), it remains challenging to distinguish between patients with favorable and unfavorable treatment-free survival (TFS). Additionally, the downstream protein correlates of well-known molecular features of CLL are not ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD036918 | Pride
Themis2 Biomarker Chronic lymphocytic leukemia 
UnknownPrognosis of IGLV3-21R110 chronic lymphocytic leukemia after chemotherapy-based treatment in a real-world analysis.
Not available
S-EPMC10457177 | biostudies-literature
TranscriptomicsTranscription profiling by array of human T-cell differentiation
To gain more insight into initiation and regulation of T cell receptor (TCR) gene rearrangement during human T cell development, we analyzed TCR gene rearrangements by quantitative PCR analysis in nine consecutive T-cell developmental stages, including CD34+ lin- cord blood cells as a reference. The...
ORGANISM(S): Homo sapiens 
2005-07-01 | E-MEXP-337 | biostudies-arrayexpress
UnknownHigh-throughput Proteomics Identifies THEMIS2 as Independent Biomarker of Treatment-free Survival in Untreated CLL.
Not available
S-EPMC10508458 | biostudies-literature
UnknownImmunoglobulin heavy-chain status and stromal interactions shape ferroptosis sensitivity in chronic lymphocytic leukemia.
Not available
S-EPMC12765864 | biostudies-literature
UnknownImpact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia.
Not available
S-EPMC9315922 | biostudies-literature
UnknownEGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.
Not available
S-EPMC7001738 | biostudies-literature
UnknownValidation of the EuroClonality-NGS DNA capture panel as an integrated genomic tool for lymphoproliferative disorders.
Not available
S-EPMC8405189 | biostudies-literature
UnknownDisease-specific U1 spliceosomal RNA mutations in mature B-cell neoplasms.
Not available
S-EPMC12380619 | biostudies-literature
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