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TranscriptomicsIdentification of the hemogenic endothelial progenitor and its direct precursor in human pluripotent stem cell differentiation cultures
Hemogenic endothelium (HE) is the source of HSCs in the developing embryo. In this study we have identified the hemogenic endothelial progenitors and their precursors originating from differentiated H1 cells on OP9 stromal cells. RNA-seq of hemogenic endothelial progenitors and their precursors ori...
ORGANISM(S): Homo sapiens 
2012-09-18 | E-GEOD-39661 | biostudies-arrayexpress
TranscriptomicsA protective strategy against hyperinflammatory responses requiring the non-transcriptional actions of GPS2
The association between hyper-inflammatory states and numerous diseases is widely recognized, but our understanding of the molecular strategies that have evolved to prevent uncontrolled activation of inflammatory responses remains incomplete. Here, we report a critical, non-transcriptional role of G...
ORGANISM(S): Homo sapiens 
2012-03-23 | E-GEOD-35197 | biostudies-arrayexpress
GenomicsChIPseq of enterocytes of the jejunum from transgene C57BL/6 mice harboring a CKIαΔgut knock-out
ChIPseq of enterocytes of the jejunum from transgene C57BL/6 mice to assess the effects of a CKIαΔgut knock-out in the jejunum and a CKIαΔgut/p53 double knock-out. In addition, enterocytes expressing a mutant p53 (R172H) in combination with CKIαΔgut knockout were analyzed.
ORGANISM(S): Mus musculus 
2020-02-25 | E-MTAB-7858 | biostudies-arrayexpress
TranscriptomicsRNA-seq of ppp1r13l knockdown in neonatal mice cardiomyocytes and lipopolysaccharide stimulation kinetics transcriptome
A novel ppp1r13l sequence variation causes dilated cardiomyopathy and cardiac inflammation. In this experiment we knocked down IASPP (protein product of ppp1r13l) in cardiomyocytes and exposed them to lipopolysaccharide for time interval of 2 and 4 hours. Transcriptome was examined using rna-seq hig...
ORGANISM(S): Mus musculus 
2017-06-13 | E-MTAB-5826 | biostudies-arrayexpress
UnknownThe landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing.
Not available
S-EPMC7983596 | biostudies-literature
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