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ProteomicsTemporal proteomic analyses of the protein contents found in the insoluble fraction of the a-synuclein PFF-treated neurons
Parkinson’s disease (PD) is characterized by the accumulation of misfolded and aggregated alpha-synuclein (α-syn) into intraneuronal inclusions named Lewy bodies (LB). Although it is widely believed that α-syn plays a central role in the pathogenesis of PD, the processes that govern α-syn fibrilliza...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-15 | PXD016850 | Pride
Mouse primary neurons 
ProteomicsProteome content of insoluble fraction of Httex1 transduced neurons
Investigate the protein content of the insoluble fraction of primary neurons transdusced with Httex1 (+/-GFP).The ultimate goal is to assess the protein contents of Httex1 transduced neurons depending on the polyQ length and the presence of a GFP tag.
ORGANISM(S): Mus musculus (Mouse) 
2021-10-08 | PXD028323 | Pride
Neurons Huntington disease Inclusions Httex1 
ProteomicsProteome content of insoluble fraction of Httex1 transfected cells
Investigate the protein content of the insoluble fraction of HEK cells transfected with Httex1 (+/-GFP).The ultimate goal is to assess the protein contents of Httex1 transfected cells depending on the polyQ length and the presence of a GFP tag.
ORGANISM(S): Homo sapiens (Human) 
2021-10-08 | PXD021742 | Pride
Httex1 inclusions hek cells urea fraction 
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