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UnknownSTAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett?s adenocarcinomas
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ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-47763 | biostudies-other
TranscriptomicsSTAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and BarrettM-bM-^@M-^Ys adenocarcinomas
Signal transducer and activator of transcription 3 (STAT3) is altered in several epithelial cancers and represents a potential therapeutic target. Here, STAT3 expression, activity and cellular functions were examined in two main histotypes of esophageal carcinomas. In situ, immunohistochemistry for ...
ORGANISM(S): Homo sapiens 
2013-06-16 | E-GEOD-47763 | biostudies-arrayexpress
TranscriptomicsCombination of HDAC inhibitors and Azacytidine for Cancer Cell Selective Targeting of Esophageal Cancer Cells
Esophageal cancers (ECs) are highly aggressive tumors with poor prognosis and few treatment options. This study investigated the possibility of treating esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC) cells by inhibitors of broad and specific histone deacetylases (HDACi...
ORGANISM(S): Homo sapiens 
2015-04-29 | E-GEOD-57130 | biostudies-arrayexpress
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