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Epigenetic changes such as DNA methylation variation are known to play a role in gene regulation and common disease susceptibility. Little is known about the genome-wide frequency, localization and function of such changes and how they are regulated by genetic and environmental factors. We have util...
ORGANISM(S): Homo sapiens 
French glioma case germline genotypes using Illumina HumanExome-12v1_A array
UK glioma case germline genotypes using Illumina HumanExome-12v1_A array
French glioma control germline genotypes using Illumina HumanExome-12v1_A array
German glioma case germline genotypes using Illumina HumanExome-12v1_A array
German glioma control germline genotypes using Illumina HumanExome-12v1_A array
To identify protein altering variants (PAVs) for glioma we analysed Illumina HumanExome BeadChip exome array data on 1,882 glioma cases and 8,079 controls from three independent European populations. In addition to single variant tests we incorporated information on the predicted functional conseque...
Data Access Committee EGAC00001000345
Aggregate results from a GWAS study on 3352 cases abd 3145 controls
An increased level of Lp(a) lipoprotein has been identified as a risk factor for coronary artery disease that is highly heritable. The genetic determinants of the Lp(a) lipoprotein level and their relevance for the risk of coronary disease are incompletely understood. METHODS: We used a novel gene c...
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