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TranscriptomicsExploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution
In this study, using a murine model of Ph+ acute lymphoblastic leukemia (Ph+ ALL), a combined pharmacological profile and drug selection experimental approach identified distinct stages of tumor clonal evolution with vulnerabilities to sets of small molecules. Through genotypic, phenotypic, signalin...
ORGANISM(S): Mus musculus 
2016-04-05 | E-GEOD-72910 | biostudies-arrayexpress
ModelsChen2009 - ErbB Signaling
This is A431 IERMv1.0 model described in the article Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data. William W Chen, Birgit Schoeberl, Paul J Jasper, Mario Niepel, Ulrik B Nielsen, Doug...
2024-09-02 | BIOMD0000000255 | BioModels
TranscriptomicsOncogene-dependent regulation of tumor cells via stromal reciprocal signalling
Cancer is a heterocellular disease composed of tumor cells and stromal cells. Although stromal cells are known to regulate cancer progression, oncogene-dependent signalling through heterocellular cancer systems remains poorly elucidated. Here, we describe KRASG12D-dependent ‘reciprocal’ signalling a...
ORGANISM(S): Mus musculus 
2015-06-27 | E-GEOD-70351 | biostudies-arrayexpress
OtherReproducible Automated Phosphopeptide Enrichment using Magnetic TiO2 and Ti-IMAC.
Data from ProteomeXchange, PXD ID: PXD000892. File: FIG5_1_KRAS_G12D_3.msf.mgf. Published as part of Anal Chem. 2014 Sep 18 . From the Abstract: {{i}} Reproducible, comprehensive phosphopeptide enrichment is essential to study phosphorylation-regulated processes. Here, we describe the application o...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM32320003560 | GPMDB
Resource Reanalysis 
UnknownMena binds α5 integrin directly and modulates α5β1 function
Not available
S-JCBD-201202079 | bioimages
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