Sort   by:  
 Page size 
ProteomicsFast open modification spectral library searching through approximate nearest neighbor indexing
Open modification searching (OMS) is a powerful search strategy that identifies peptides carrying any type of modification by allowing a modified spectrum to match against its unmodified variant by using a very wide precursor mass window. A drawback of this strategy, however, is that it leads to a l...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2021-05-25 | PXD009861 | Pride
Ptm Open modification searching Spectral library 
ProteomicsExtremely fast and accurate open modification spectral library searching of high-resolution mass spectra using feature hashing and graphics processing units
Open modification searching (OMS) is a powerful search strategy to identify peptides with any type of modification. OMS works by using a very wide precursor mass window to allow modified spectra to match against their unmodified variants, after which the modification types can be inferred from the c...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2019-12-06 | PXD013641 | Pride
Proteomics Graphics processing unit Post-translational modification Mass spectrometry Feature hashing Approximate nearest neighbor indexing Spectral library Open modification searching 
ProteomicsMulti-omics reveals molecular responses to aneuploidy in Leishmania
Integrated genomics, transcriptomics, proteomics and metabolomics experiment of aneuploid Leishmania donovani strains. This submission concerns the proteomic data.
ORGANISM(S): Leishmania donovani Ld 2001 
2022-08-26 | PXD028521 | Pride
Leishmania aneuploidy multiomics proteomics 
MetabolomicsIntegrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent

Leishmania donovani is the responsible agent for visceral leishmaniasis (VL) in the Indian subcontinent (ISC). The disease is lethal without treatment and causes 0.2 to 0.4 million cases each year. Recently, reports of VL in Nepalese hilly districts have increased as well as VL cases cau...

2022-09-15 | MTBLS1606 | MetaboLights
TranscriptomicsDietary flavanols modulate the transcription of genes involved in cardiovascular pathology with complex changes of their DNA methylation state
Background: In a recent intervention study, the daily supplementation with 200 mg monomeric and oligomeric flavanols (MOF) from grape seeds for 8 weeks revealed a vascular health benefit in male smokers. The objective of the present study was to determine the impact of MOF consumption on the gene ex...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-54643 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of drought treated P.euphratica
Plantlets of P. euphratica (clone B2) were obtained by in vitro culture. After ex vitro acclimation, they were transferred and acclimated to greenhouse conditions and transplanted into 7.5L-pot filled with peat-sand mix (50/50 V/V) and were pruned (following some leaf shedding due to transplantation...
ORGANISM(S): Populus euphratica 
2005-03-01 | E-MEXP-276 | biostudies-arrayexpress
MetabolomicsFour layer multi-omics reveals molecular responses to aneuploidy in Leishmania

Aneuploidy causes system-wide disruptions in the stochiometric balances of transcripts, proteins, and metabolites, often resulting in detrimental effects for the organism. The protozoan parasite Leishmania has an unusually high tolerance for aneuploidy, but the molecular and functional consequenc...

2022-09-19 | MTBLS1612 | MetaboLights
Sort   by:  
 Page size