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TranscriptomicsTranscription profiling of drought treated P.euphratica
Plantlets of P. euphratica (clone B2) were obtained by in vitro culture. After ex vitro acclimation, they were transferred and acclimated to greenhouse conditions and transplanted into 7.5L-pot filled with peat-sand mix (50/50 V/V) and were pruned (following some leaf shedding due to transplantation...
ORGANISM(S): Populus euphratica 
2005-03-01 | E-MEXP-276 | biostudies-arrayexpress
ProteomicsTEAD inhibitor K-975 enhances KRASG12C inhibitor adagrasib-mediated cancer cell proliferation inhibition via dual cell cycle arrest
Here we investigate the effect of the dual inhibition, in KRASG12C mutated NSCLC cells, using the KRASG12Ci adagrasib (MRTX849) and the pan-TEAD inhibitor (TEADi) K-975. We show that K-975 enhances adagrasib-induced tumor cell growth inhibition in cancer cells. Mechanistically, we detect a downregul...
ORGANISM(S): Homo Sapiens (human) 
2023-05-12 | PXD039726 | JPOST Repository
UnknownSmall airways diseases, excluding asthma and COPD: an overview.
Not available
S-EPMC9487373 | biostudies-literature
TranscriptomicsTranscriptomic profiling of lung monocytes and macrophages in mice
We developed a simplified flow cytometry strategy in order to discriminate monocytes and macrophages in the lung of C57BL/6 mice. Using this strategy, we identified autofluorescent F4/80+ CD11c+ alveolar macrophages, non-autofluorescent CD64+Ly-6C- interstitial macrophages and Ly-6Chi monocytes resi...
ORGANISM(S): Mus musculus 
2017-03-01 | E-MTAB-5012 | biostudies-arrayexpress
UnknownPhysiological Evaluation of Anomalous Aortic Origin of a Coronary Artery Using Computed Tomography-Derived Fractional Flow Reserve.
Not available
S-EPMC8174353 | biostudies-literature
TranscriptomicsCotranscriptional exon skipping in the genotoxic stress response
Pre-mRNA splicing is functionally coupled to transcription, and genotoxic stresses can enhance alternative exon inclusion by affecting elongating RNA polymerase II. We report here that various genotoxic stress inducers, including camptothecin, inhibit the interaction between EWS, an RNA polymerase I...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-21840 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of early response of rat brain orthotopic tumors after synchrotron microbeam irradiation (MRT)
The aim of this study was to identify the transcriptomic response 6 hours after the MRT irradiation, in normal brain tissue (11 samples) and in glioma tissue (11 samples), in rat. The orthotopic tumor-bearing rats were either treated with MRT radiation (six MRT-tumors), or untreated (five No irradia...
ORGANISM(S): Rattus norvegicus 
2015-09-01 | E-GEOD-50478 | biostudies-arrayexpress
UnknownRisk factors for early mortality from lung cancer: evolution over the last 20 years in the French nationwide KBP cohorts.
Not available
S-EPMC11214995 | biostudies-literature
TranscriptomicsRNA helicases DDX5 and DDX17 dynamically orchestrate transcription, microRNA and splicing programs in cell differentiation
RNA helicases DDX5 and DDX17 are members of a large family of highly conserved proteins involved in gene expression regulation, although their in vivo targets and activities in biological processes like cell differentiation, that requires reprogramming of gene expression programs at multiple levels,...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-57281 | biostudies-arrayexpress
UnknownRivaroxaban vs Vitamin K Antagonist in Patients With Atrial Fibrillation and Advanced Chronic Kidney Disease.
Not available
S-EPMC11198259 | biostudies-literature
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