Laurent K K - OmicsDI

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Unknown (643)
Transcriptomics (78)
Proteomics (26)
Genomics (13)
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Organisms

Homo sapiens (65)
Mus musculus (18)
Bos taurus (5)
Saccharomyces cerevisiae (4)
Arabidopsis thaliana (4)
Vitis vinifera (3)
Rattus norvegicus (2)
Drosophila melanogaster (2)
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Leishmania major (1)
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Salmo salar (1)
Glycine max (1)
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Apis mellifera (1)
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Lacticaseibacillus casei BL23 (1)
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Streptomyces coelicolor (1)
Theileria annulata strain Ankara (1)

Repository

biostudies-arrayexpress (87)
pride (20)
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Breast adenocarcinoma (2)
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Mass Spectrometry (20)
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Instrument Platform

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UNIPROT ID/AC

1433B_HUMAN (1)
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1433S_HUMAN (1)
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8ODP_HUMAN (1)
9606.ENSP00000233596 (1)
9606.ENSP00000268624 (1)
9606.ENSP00000291295 (1)
9606.ENSP00000299157 (1)
9606.ENSP00000330842 (1)
9606.ENSP00000331127 (1)
9606.ENSP00000343200 (1)
9606.ENSP00000347168 (1)
9606.ENSP00000348924 (1)

CHEBI ID

CHEBI:15354 (2)
CHEBI:15366 (2)
CHEBI:16449 (2)
CHEBI:16704 (2)
CHEBI:16811 (2)
CHEBI:16870 (2)
CHEBI:17750 (2)
CHEBI:17790 (2)
CHEBI:18237 (2)
CHEBI:24898 (2)
CHEBI:30751 (2)
CHEBI:32816 (2)
CHEBI:78320 (2)
CHEBI:10014 (1)
CHEBI:10015 (1)
CHEBI:10016 (1)
CHEBI:10019 (1)
CHEBI:10093 (1)
CHEBI:10443 (1)
CHEBI:10577 (1)
CHEBI:110 (1)
CHEBI:131762 (1)
CHEBI:132656 (1)
CHEBI:132659 (1)
CHEBI:132663 (1)
CHEBI:132666 (1)
CHEBI:132668 (1)
CHEBI:132669 (1)
CHEBI:132696 (1)
CHEBI:132950 (1)

Metabolite Name

Acetate (2)
Alanine (2)
Betaine (2)
Choline (2)
Formate (2)
Glutamate (2)
Glycerophosphocholine (2)
Isoleucine (2)
Lactate (2)
Methanol (2)
Methionine (2)
Pyruvate (2)
Succinate (2)
Uridine (2)
(+)-Camphor (1)
(+)-beta-Selinene (1)
(S)-(-)-Citronellic acid, methyl ester (1)
1(10),11-Eremophiladien-9-ol (1)
1,4-Benzenedipropanol, alpha,alpha',gamma,gamma,gamma',gamma'-hexamethyl- (1)
1-Amino-2-Ethoxybenzene (1)
1-Naphthylamine (1)
1-[1-Methoxy-3,3-dimethyl-2-(3-methylbuta-1,3-dienyl)cyclopentyl]ethanone (1)
10-Isopropenyl-3,7-cyclodecadien-1-one (1)
10-hydroxygeissoschizol (1)
10-hydroxyusambarensine (1)
10-hydroxyusambarine (1)
11-hydroxyusambarine (1)
11-methoxyyohimbine (1)
14,15-dehydrovincamine (1)
18,19-dihydrousambarine (1)

IsPrivate

False (1)

Modelling Approach

Ordinary differential equation model (1)

Study type

Transcription profiling by array (57)
Comparative genomic hybridization by array (6)
ChIP-seq (5)
RNA-seq of coding RNA (5)
Unknown experiment type (3)
Transcription profiling by SAGE (2)
Animal - One-color microarray (2)
Methylation profiling by array (2)
Methylation profiling by high throughput sequencing (2)
Genotyping by array (1)

Release Date

2022 (89)
2021 (84)
2025 (80)
2023 (57)
2024 (50)
2015 (37)
2019 (37)
2020 (35)
2014 (33)
2018 (32)
2012 (31)
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2013 (25)
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2009 (13)
2011 (12)
2026 (12)
2008 (11)
2007 (7)
2005 (4)
2006 (3)
2004 (3)
2003 (2)
2002 (2)
2001 (2)

Lab affiliation

Univ. Lille, Inserm, CHU Lille, U1192 - Protéomique Réponse Inflammatoire Spectrométrie de Masse - PRISM, F-59000 Lille, France (3)
Proteomic Facility, Institut Jacques Monod, UMR7592 (CNRS and Paris University) (2)
Applied Research Department, LAM Biotechnologies SA, CH-1066 Épalinges, Switzerland Regenerative Therapy Unit, Lausanne University Hospital, University of Lausanne, CH-1066 Épalinges, Switzerland (1)
Cambridge Centre for Proteomics Cambridge System Biology Centre Wellcome Trust Stem Cell building University of Cambridge Department of Biochemistry Tennis Court Road Cambridge CB2 1QR (1)
Cambridge Centre for Proteomics University of Cambridge (1)
Department of Biochemistry University of Cambridge (1)
Department of Ecology and Evolution, University of Lausanne, CH-1015 Lausanne, Switzerland (1)
Dept. of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden; Clinical proteomics mass spectrometry, Science for Life Laboratory, Sweden (1)
Département d'écologie et évolution Université de Lausanne Bâtiment Biophore CH-1015 Lausanne Switzerland (1)
EDyP (1)
IMP - Research Institute of Molecular Pathology Campus-Vienna-Biocenter 1 1030 Vienna Austria (1)
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France; University of Paris, Imagine Institute, Paris, France; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA; Department of Pediatrics, Necker Hospital for Sick Children, AP-HP, Paris, France; Howard Hughes Medical Institute, New York, NY, USA (1)
St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, New York, USA. (1)
Team SOAP, CRCI2NA, Nantes University, INSERM, CNRS, Université d’Angers, Nantes, France / Equipe Labellisée Ligue Contre le Cancer, France (1)
Translational Genomic Research Institute (1)
UMR CNRS 8200, Institut Gustave Roussy, Université Paris-Saclay, Villejuif, France (1)
USR3149 CNRS - ESPCI ParisTech (1)

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TEAD inhibitor K-975 enhances KRASG12C inhibitor adagrasib-mediated cancer cell proliferation inhibition via dual cell cycle arrest

Here we investigate the effect of the dual inhibition, in KRASG12C mutated NSCLC cells, using the KRASG12Ci adagrasib (MRTX849) and the pan-TEAD inhibitor (TEADi) K-975. We show that K-975 enhances adagrasib-induced tumor cell growth inhibition in cancer cells. Mechanistically, we detect a downregul...

ORGANISM(S): Homo Sapiens (human)

2023-05-12 | PXD039726 | JPOST Repository

HDAC6 and SIRT2 regulate the acetylation state and oncogenic activity of mutant K-RAS.

Not available

S-EPMC3778089 | biostudies-literature

Kras mutant v WT with or without AZD6244 in vivo study

HCT116 (kRas mt) cells and HKH2 (Kras wt) cells were implanted into the right and left flanks of nude mice and either untreated or treated with a MEK inhibitor (AZD6244) over time. Tumours were excised and harvested for RNA extraction at the end of the experiment and hybridised to the Colorectal DS...

ORGANISM(S): Homo sapiens

2012-04-30 | E-MEXP-3557 | biostudies-arrayexpress

Rivaroxaban vs Vitamin K Antagonist in Patients With Atrial Fibrillation and Advanced Chronic Kidney Disease.

Not available

S-EPMC11198259 | biostudies-literature

The role of deep convection and nocturnal low-level jets for dust emission in summertime West Africa: Estimates from convection-permitting simulations.

Not available

S-EPMC4394720 | biostudies-literature

Transcription regulation coupling of the divergent argG and metY promoters in Escherichia coli K-12.

Not available

S-EPMC154083 | biostudies-literature

Hodge theory-based biomolecular data analysis.