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TranscriptomicsA Molecular Taxonomy of Urothelial Carcinoma
Even though urothelial cancer (UC) is the fourth common tumor type among males, progress in treatment development has been deficient. Pathological assessment provides the urologists with only a broad classification, complicated by frequent disagreement among pathologist and the co-existence of diffe...
ORGANISM(S): Homo sapiens 
2012-05-23 | E-GEOD-32894 | biostudies-arrayexpress
TranscriptomicsDNA methylation analyses of urothelial carcinoma reveal distinct epigenetic subtypes and an association between gene copy number and methylation status
We assessed DNA methylation and copy number status of 27,000 CpGs in 149 urothelial carcinomas and integrated the findings with gene expression and mutation data. Methylation was associated with gene expression for 1,332 CpGs, of which 26% showed positive correlation with expression, i.e., high meth...
ORGANISM(S): Homo sapiens 
2012-08-31 | E-GEOD-33510 | biostudies-arrayexpress
TranscriptomicsIntegrated genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma (gene expression)
Genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma 131 primary bladder cancer tumor samples were analyzed on Illumina gene expression Bead Arrays.
ORGANISM(S): Homo sapiens 
2012-06-17 | E-GEOD-32548 | biostudies-arrayexpress
TranscriptomicsGenome-wide DNA methylation analysis of lung carcinoma
Lung cancer is the worldwide leading cause of death from cancer. DNA methylation in gene promoter regions is a major mechanism of gene expression regulation that may promote tumorigenesis. However, whether clinically relevant subgroups based on DNA methylation patterns exist in lung cancer is not we...
ORGANISM(S): Homo sapiens 
2014-10-05 | E-GEOD-56044 | biostudies-arrayexpress
TranscriptomicsDNA methylation in melanoma is connected to gene expression phenotypes and MITF pathway expression.
We subjected 50 stage III/IV tumors and 9 melanoma cell lines to genome-wide methylation analysis using the Illumina Infinium Human Methylation450 BeadChip. Furthermore, we used two technical replicates of light, medium, dark melanocyte, dermal epidermis and fibroblasts (Science Cell Research, USA),...
ORGANISM(S): Homo sapiens 
2015-05-17 | E-GEOD-51547 | biostudies-arrayexpress
TranscriptomicsIntegrated genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma (genomic)
Genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma 146 primary bladder cancer tumor samples were analyzed on BAC array containing ~32 000 BAC clones. Arrays were produced at the Swegene Centre for Integrative Biology at Lund University ...
ORGANISM(S): Homo sapiens 
2012-06-17 | E-GEOD-32535 | biostudies-arrayexpress
UnknownThe clinicopathological and gene expression patterns associated with ulceration of primary melanoma.
Not available
S-EPMC4276506 | biostudies-literature
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