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GenomicsInsulator dysfunction and oncogene activation in IDH mutant gliomas
Gain-of-function IDH mutations define major clinical and prognostic classes of gliomas. Mutant IDH protein produces a novel onco-metabolite, 2-hydroxyglutarate (2-HG), that interferes with iron-dependent hydroxylase enzymes, including the TET family of 5'-methylcytosine hydroxylases. TET enzymes are...
ORGANISM(S): Homo sapiens 
2015-12-23 | E-GEOD-70991 | biostudies-arrayexpress
ModelsBenedict2011 - Genome-scale metoblic network of Methanosarcina acetivorans (iMB745)
Benedict2011 - Genome-scale metoblic network of Methanosarcina acetivorans (iMB745) This model is described in the article: Genome-scale metabolic reconstruction and hypothesis testing in the methanogenic archaeon Methanosarcina acetivorans C2A. Benedict MN, Gonnerman MC, Metc...
2024-10-15 | BIOMD0000001097 | BioModels
FROG 
TranscriptomicsmRNA Sequencing Reveals Altered Synaptic Vesicular Transport in Post-Mortem Cerebellum
Schizophrenia (SCZ) is a common, disabling mental illness with high heritability but complex, poorly understood genetic etiology. As the first phase of a genomic convergence analysis of SCZ, we generated 16.7 billion nucleotides of short read, shotgun sequences of cDNA from post-mortem cerebellar c...
ORGANISM(S): Homo sapiens 
2009-08-29 | E-GEOD-12297 | biostudies-arrayexpress
UnknownThe genomic landscape of 2,023 colorectal cancers.
Not available
S-EPMC11374690 | biostudies-literature
UnknownClinical complexity and impact of the ABC (Atrial fibrillation Better Care) pathway in patients with atrial fibrillation: a report from the ESC-EHRA EURObservational Research Programme in AF General Long-Term Registry.
Not available
S-EPMC9440492 | biostudies-literature
UnknownThe Future of Women in Psychological Science.
Not available
S-EPMC8114333 | biostudies-literature
UnknownIdentification of genes required for eye development by high-throughput screening of mouse knockouts.
Not available
S-EPMC6303268 | biostudies-literature
UnknownCerebral small vessel disease genomics and its implications across the lifespan.
Not available
S-EPMC7722866 | biostudies-literature
UnknownWhole-genome sequencing reveals host factors underlying critical COVID-19.
Not available
S-EPMC9259496 | biostudies-literature
UnknownGWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Not available
S-EPMC10208981 | biostudies-literature
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