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ProteomicsEggs of the mosquito Aedes aegypti survive desiccation by rewiring their polyamine and lipid metabolism
Upon water loss, some organisms pause their life cycles and escape death. While widespread in microbes, this is less common in animals. Aedes mosquitoes are vectors for viral diseases. Aedes eggs can survive dry environments, but molecular and cellular principles enabling egg survival through desicc...
ORGANISM(S): Aedes aegypti aegypti 
2023-09-26 | PXD044525 | Pride
Lipid metabolism Regeneration Metabolic rewiring Aedes mosquito Desiccation 
ProteomicsRegulation of Far11 phosphorylation by Ppg1 phosphatase
Ppg1 phosphatase post-translationally regulates Far11. To identify Far11 phosphorylation sites regulated by Ppg1, we immunopurified Far11 from wild-type and Ppg1 catalytically inactive (Ppg1-H111N) cells. We used this immunopurified Far11 for proteomics and identified Ppg1 dependent Far11 phosphoryl...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-02-29 | PXD049989 | Pride
Immunopurification Glucose signaling Phosphorylation Phosphatase 
ProteomicsIdentification of interacting partners of Ppg1 phosphatase
PP2A-like phosphatase Ppg1 was identified as a regulator of carbon metabolism and enabled adaption to glucose depletion. To elucidate the molecular mechanism, we immunopurified Ppg1 and identified its interacting proteins by mass spectrometry based proteomics.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-02-29 | PXD049793 | Pride
Glucose signaling Protein-protein interaction Phosphatase Metabolic adaptation 
UnknownBiochemical curiosities : Piquing students' interest in biochemistry by exploring evolution's pursuit of the improbable.
Not available
S-EPMC11467204 | biostudies-literature
UnknownThe E3 ubiquitin ligase Pib1 regulates effective gluconeogenic shutdown upon glucose availability.
Not available
S-EPMC6873170 | biostudies-literature
UnknownMethionine uptake via the SLC43A2 transporter is essential for regulatory T-cell survival.
Not available
S-EPMC9463494 | biostudies-literature
UnknownAn economic demand-based framework for prioritization strategies in response to transient amino acid limitations.
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S-EPMC11344141 | biostudies-literature
UnknownMethylated PP2A stabilizes Gcn4 to enable a methionine-induced anabolic program.
Not available
S-EPMC7939465 | biostudies-literature
UnknownSARS-CoV-2 variants: Impact on biological and clinical outcome.
Not available
S-EPMC9685312 | biostudies-literature
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