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A ""Cartes d'Identite des Tumeurs"" (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). 65 samples on Affymetrix HG-U133A GeneChips arrays (57 tumoral samples, 3 hepatocellular adenomas, 5 non-tumoral pools). Identification of six subgroups of Hepatocellular...
ORGANISM(S): Homo sapiens 
Human acute myeloid leukemia HL60 cells were transduced with IDH1-WT or IDH1-R132H, and corresponding sub-clones were generated by FACS. In a first series of experiments, cells expressing wt and mutant IDH1were treated with either 1µM all-trans retinoic acid (ATRA) or with vehicle (DMSO) for 24 hrs...
ORGANISM(S): Homo sapiens 
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