Sort   by:  
 Page size 
ProteomicsmPFC Synaptosome Proteomics Reveals Novel Pathways and Muscarinic Receptor Changes in a Learned Helplessness Mouse Model
Stressful events are a leading factor in development of depression. The medial prefrontal cortex (mPFC) is strongly associated with depression etiology and exposure to uncontrollable stressors results in synaptic dysfunction and loss. Learned helplessness is a behavioral paradigm that measures effec...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-20 | PXD073765 | Pride
Mpfc Acetylcholine Major depressive disorder Stress models Learned helplessness Muscarinic receptors Proteomics 
Genomicssingle cell RNA Sequencing of hippocampi of mice subjected or not to the learned helplessness paradigm
single cell RNA Sequencing of hippocampi of mice subjected or not to the learned helplessness paradigm
PRJNA694767 | ENA
Transcriptomicssingle cell RNA Sequencing of hippocampi of mice subjected or not to the learned helplessness paradigm
The goal of the study was to identify the hippocampal microenvironment asscoaited with stress, in particular stress-induced learned helplessness. By comparing chronic and acute induction of learned helplessness, we identified cell populations and genes associated with resilience.
ORGANISM(S): Mus musculus 
2023-06-30 | GSE165507 | GEO
TranscriptomicsLearned Helplessness Regulates Synapse Related LncRNAs in Mouse Hippocampus
Purpose: RNA sequencing (RNA-Seq) has revolutionized systems-based analysis of cellular pathways. The goal of this study is to find learned helplessness/depression regulates synapse related long noncoding RNAs (lncRNAs) in mouse hippocampus Methods: compared the differential expression of mRNA and l...
ORGANISM(S): Mus musculus 
2017-08-24 | GSE102965 | GEO
GenomicsMus musculus
Learned Helplessness Regulates Synapse Related LncRNAs in Mouse Hippocampus
PRJNA399643 | ENA
UnknownSpike firing attenuation of serotonin neurons in learned helplessness rats is reversed by ketamine.
Not available
S-EPMC8688795 | biostudies-literature
UnknownC1q deletion exacerbates stress-induced learned helplessness behavior and induces neuroinflammation in mice.
Not available
S-EPMC8807734 | biostudies-literature
UnknownParental Stress, Learned Helplessness, and Perceived Social Support in Mothers of Children with Hearing Loss and Mothers of Typically Developing Children.
Not available
S-EPMC11755561 | biostudies-literature
UnknownInescapable Stress Changes Walking Behavior in Flies - Learned Helplessness Revisited.
Not available
S-EPMC5119826 | biostudies-literature
UnknownWhole-Brain Mapping of Neuronal Activity in the Learned Helplessness Model of Depression.
Not available
S-EPMC4737884 | biostudies-literature
Sort   by:  
 Page size